Benzodiazepine-Based Drug Discovery
Elsevier Science Publishing Co Inc (Verlag)
978-0-12-824516-3 (ISBN)
The importance of these privileged pharmacophores is not limited to the treatment of psychotic disorders because minor changes in the structures can generate various biological activities. They represent a wide range of therapeutic functions such as anticonvulsant, antianxiety, anti-depressant, antiviral, anti-HIV, anti-inflammatory, anticoagulant, anti-obesity, endothelin antagonist, cholecystokinin antagonist, and vasopressin receptor antagonist activities.
Farzad Zamani obtained his PhD from University of Wollongong (Australia) in 2019 under the supervision of Professor Stephen Pyne and Dr. Christopher Hyland. His research included development of transition metal-catalyzed cyclization reactions and heterocycle synthesis. Currently, he is a JSPS postdoctoral fellow in the group of Professor Takayoshi Suzuki at Osaka University working on investigation of small molecule inhibitors of RNA/epigenetic protein complexes in drug discovery.Farzad Zamani obtained his PhD from University of Wollongong (Australia) in 2019 under the supervision of Professor Stephen Pyne and Dr. Christopher Hyland. His research included development of transition metal-catalyzed cyclization reactions and heterocycle synthesis. Currently, he is a JSPS postdoctoral fellow in the group of Professor Takayoshi Suzuki at Osaka University working on investigation of small molecule inhibitors of RNA/epigenetic protein complexes in drug discovery. Esmail Doustkhah received his PhD in 2017 in the field of catalysis and organic chemistry. In his PhD, he received several awards and scholarships. Currently, he is a JSPS fellow at NIMS in the group of Professors Y. Yamauchi and Y. Ide. His research areas include silicate nanosheet, mesoporous materials, and titania nanostructures for (photo)(bio)catalysis.
1. An Introduction to Benzodiazepines 2. Chemical Structure of 1,4-Benzodiazepines 3. Synthesis of 1,4-Benzodiazepines 4. Biological Behavior of 1,4-Benzodiazepines 5. Pharmaceutical Applications of 1,4-Benzodiazepines 6. Chemical Structure of 1,5-Benzodiazepines and 1,5-Benzothiazepines 7. Synthesis of 1,5-Benzodiazepines and 1,5-Benzothiazepines 8. Biological Behavior of 1,5-Benzodiazepines and 1,5-Benzothiazepines 9. Pharmaceutical Applications of 1,5-Benzodiazepines 10. Pharmaceutical Applications of 1,5-Benzothiazepines
Erscheinungsdatum | 26.08.2022 |
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Reihe/Serie | Heterocyclic Drug Discovery |
Zusatzinfo | Approx. 100 illustrations; Illustrations, unspecified |
Sprache | englisch |
Maße | 152 x 229 mm |
Gewicht | 540 g |
Themenwelt | Naturwissenschaften ► Chemie ► Organische Chemie |
ISBN-10 | 0-12-824516-6 / 0128245166 |
ISBN-13 | 978-0-12-824516-3 / 9780128245163 |
Zustand | Neuware |
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