Lymphatic Transport of Drugs

William N Charman

Introduction/Preface (W. N. Charman and V. J. Stella). Anatomy and Physiology of the Lymphatics (C.M. O'Driscoll). Intestinal Processing of Dietary Lipids (C.M. Mansbach,II). Methodologies for the Assessing Intestinal Lymphatic Transport (T.J. Raub, S.L. Douglas, G.W. Melchior, W.N. Charman, and W. Morozowich). Lipid Vehicle and Formulation Effects on Intestinal Lymphatic Drug Transport (W.N. Charman). Lipophilic Prodrugs and the Promotion of Intestinal Lymphatic Drug Transport (V.J. Stella and N.L. Pochopin). The Clearance of Lipoproteins and of Drugs Associated with Lipoproteins (T. Noguchi). Lymphatic Transport of Polar Drugs After Gastrointestinal Dosing (H. Yoshikawa and S. Muranishi). Lymphatic Transport After Parenteral Drug Administration (Y. Takakura, M. Hashida, and H. Sezaki). Particulates and Lymphatic Drug Delivery (D.T. O'Hagan, N.M. Christy, and S.S. Davis).