Microglia
Humana Press Inc. (Verlag)
978-1-4939-9660-5 (ISBN)
Authoritative and cutting-edge, Microglia: Methods and Protocols serves as a vital guide to these important cells and an inspiration for scientists interested in expanding our knowledge of their role in the nervous system.
Microglia: The Neural Cells of Non-Neural Origin.- Morphology of Microglia across Contexts of Health and Disease.- Physiology of Microglia.- Microglia Reactivity: Heterogeneous Pathological Phenotypes.- Microglia in Neurodegenerative Disorders.- Physiological Implications of Microglia-Synapse Interactions.- Ultrastructural Analyses of Microglial Interactions with Synapses.- Visualizing Dark Microglia.- Electrophysiological Investigation of Microglia.- Replenishment of Organotypic Hippocampal Slice Cultures with Neonatal or Adult Microglia.- Assessment of Parasite-Microglia Interactions In Vitro.- In Vivo Visualization of Microglia Using Tomato Lectin.- Long-Term In Vivo Imaging of Individual Microglial Cells.- Analysis of Signaling Mechanisms Regulating Microglial Process Movement.- Measuring Microglial Turnover in the Adult Brain.- Novel Microglia Depletion Systems: A Genetic Approach Utilizing Conditional Diphtheria Toxin Receptor Expression and a Pharmacological Model Based on the Blocking of Macrophage Colony-Stimulating Factor 1 Receptor.- Single Cell Electroporation for Measuring In Vivo Calcium Dynamics in Microglia.- Labeling Microglia with Genetically-Encoded Calcium Indicators.- Calcium Imaging of Microglial Network Activity in Stroke.- In Vivo Two Photon Imaging of Microglial Synapse Contacts.- In Vivo Phagocytosis Analysis of Amyloid Beta.- Functional Analysis of Brain-Engrafted Monocytes after Microglial Ablation in Mouse Models.- Analysis of the Microglial Sensome.- Transcriptomics and Live Imaging to Define Functional Phenotypes of Microglia in Pathological Human Tissue.
Erscheinungsdatum | 28.08.2020 |
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Reihe/Serie | Methods in Molecular Biology ; 2034 |
Zusatzinfo | 6 Illustrations, color; 59 Illustrations, black and white; XII, 340 p. 65 illus., 6 illus. in color. |
Verlagsort | Totowa, NJ |
Sprache | englisch |
Maße | 178 x 254 mm |
Themenwelt | Studium ► Querschnittsbereiche ► Infektiologie / Immunologie |
Naturwissenschaften ► Biologie ► Biochemie | |
Naturwissenschaften ► Biologie ► Humanbiologie | |
Schlagworte | Brain immunity • Cognitive ability • Functional brain networks • Immune mediators • Microglial research • Synaptic contacts |
ISBN-10 | 1-4939-9660-6 / 1493996606 |
ISBN-13 | 978-1-4939-9660-5 / 9781493996605 |
Zustand | Neuware |
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