Genetic Damage in Human Spermatozoa

Dr. Baldi started to work in sperm biology in 1990, by studying several aspect of sperm functions as well as DNA damage. She published 155 publications in IF journals with peer review.  She has been invited as speaker in many National and International Congresses and Symposia.  She is currently associate professor of Clinical Pathology at the University of Florence and responsible of the Laboratory of semen analysis and semen cryopreservation of the Azienda Ospedaliera-Universitaria Careggi

Genetic factors affecting sperm chromatin structure.- Mechanisms of origin of chromosome deletions and rearrangements in spermatozoa.- The sperm epigenome: implications for ART outcomes.- Epigenetic transgenerational inheritance.- Environmental genetic and epigenetic sperm alterations.- Sperm DNA fragmentation: mechanisms of origin.- Sperm DNA fragmentation: consequences for reproduction.- Oxidative damage to sperm DNA: attack and defence.- Interventions to prevent sperm DNA damage effects on reproduction.-Cryopreservation of sperm: effects on chromatin and strategies to prevent them.- Effect on sperm DNA quality following sperm selection for ART: new insights.- Sperm DNA damage in cancer patients.- Index.