Supramolecular Protein Chemistry

After graduating with first class honours in chemistry Peter joined the laboratory of Prof. G. W. Canters at Leiden University, The Netherlands. Working with his advisor Prof. M. Ubbink, he used NMR spectroscopy to study transient protein interactions involved in electron transport. This research was summarized in an invited paper in Accounts of Chemical Research. From the Netherlands Peter headed south for sunnier climes. With a Marie Curie Postdoctoral fellowship he joined the lab of Prof. M. A. Carrondo at Universidade Nova de Lisboa, Portugal. During this time he further developed his interest in molecular recognition. In particular, he demonstrated the importance of cation-pi interactions in protein interfaces. In 2006, Peter returned to Ireland, working as a lecturer in Biochemistry at UCD, and since 2008 as a lecturer in Chemistry at NUI Galway. He was promoted in 2014 to Senior Lecturer and in 2017 to Personal Professor.  Current interests include protein self assembly and protein interactions under physiological conditions.

Supramolecular Approaches to Protein Recognition;

Macrocycles for Recognition and Sensing of Histone Modifications;

Sequence Predictive Recognition of Proteins and Peptides by synthetic and Natural Receptors;

Protein Modulation by Cucurbiturils;

Supramolecular Nanoassemblies Based on Proteins and Cyclodextrin Derivatives;

Molecular Tweezers and Clips that Modify Protein Function;

Molecular Glues for Protein Assembly;

The Inducing Ligand Strategy for Supramolecular Protein Assembly;

Functional Protein-(Bio)Polymer Assemblies