Animal Models of Diabetes

Practical Considerations when Using Mouse Models of Diabetes.- An Overview of Rodent Models of Obesity and Type 2 Diabetes.- Selectively Bred Diabetes Models: GK Rats, NSY Mice, and ON Mice.- A Review of Mouse Models of Monogenic Diabetes and ER Stress Signalling.- Rat Models of Human Type 1 Diabetes.- Mouse Models of Autoimmune Diabetes: The Non-Obese Diabetic (NOD) Mouse.- Mouse Models of Virus-Induced Type 1 Diabetes.- Rat Models of Virus-Induced Type 1 Diabetes.- Large Animal Models of Diabetes.- Use of Streptozotocin in Rodent Models of Islet Transplantation.- Transplantation of Islets of Langerhans into the Anterior Chamber of the Eye for Longitudinal In Vivo Imaging.- Multicolor Labeling and Tracing of Pancreatic Beta-Cell Proliferation in Zebrafish.- Generating Beta-Cell Specific Transgenic Mice Using the Cre-Lox System.- The Glucose Tolerance Test in Mice.- Assessment of Insulin Tolerance In Vivo in Mice.- Continuous Glucose Monitoring in Conscious Unrestrained Mice.- Assessing Mouse Islet Function.- Assessing Immune Responses in the Nonobese Diabetic Mouse Model of Type 1 Diabetes.- Assessment of Insulin Tolerance Ex Vivo.- Using Pancreas Tissue Slices for the Study of Islet Physiology.- Determining Beta Cell Mass, Apoptosis, Proliferation, and Individual Beta Cell Size in Pancreatic Sections.