Serpins

Overview of Serpins and Their Role in Biological Systems.- Methods for Determining and Understanding Serpin Structure and Function: X-Ray Crystallography.- Serpin Phage Display: Use of a T7 System to Probe Reactive Centre Loop Libraries with Different Serine Proteinases.- Kinetic Measurement of Serpin Inhibitory Activity by Real-Time Fluorogenic Biochemical Assay.- Methods for Identifying Virus-Derived Serpins.- In Vitro Approaches for the Assessment of Serpin Polymerization.- Cellular Models for the Serpinopathies.- Binding of Serpins to Immobilized Phospholipids and Phospholipids in Suspension.- Viral Serpin Reactive Center Loop (RCL) Peptides: Design and Testing.- In Vivo Analysis of Alpha 1 Antitrypsin Functions in Autoimmune Disease Models.- Analysis of In Vivo Serpin Functions in Models of Inflammatory Vascular Disease.- In Vivo Analysis of Alpha 1 Antitrypsin Functions in Autoimmune Disease Models.- Serpins in Venous Thrombosis and Venous Thrombus Resolution.- Next Generation Sequencing Library Preparation for 16S rRNA Microbiome Analysis after Serpin Treatment.- Methods for Assessing Serpins as Neuroprotective Therapeutics.- Serpins: Development as Clinical Therapeutics.- Serine Protease Assays: Measuring the Enzyme Targets for Serpins, Serine Protease Inhibitors.