Activated Charcoal in Medical Applications

Cooney, David O.

IntroductionHistorical Background of Activated CharcoalFundamentals of Activated Charcoal and the Adsorption ProcessProperties of Antidotal CharcoalThe Nature of Drug Absorption, Distribution, and EliminationBasic Details of Pharmacokinetic ModelingMethods for Treating Poisoning and Drug OverdoseThe Design of Clinical Studies and Data TreatmentSome Basic Aspects of Antidotal CharcoalThe Classic Studies of AndersenEffects of Activated Charcoal on Major Classes of Drugs and ChemicalsEffect of Charcoal on Other Classes of DrugsEffect of Administration Time, Food, and Gastric pHEffect of Multiple Doses of CharcoalIpecac, Cathartics, and Charcoal: Interactions and Comparative EfficaciesThe Development of Palatable FormulationsHazards Associated with Antidotal Charcoal UseEffect of Charcoal on Various Inorganic SubstancesEffect of Charcoal on Endogenous BiochemicalsUse of Charcoal to Treat Poisoning in AnimalsReports from the Soviet UnionResins and Clays as SorbentsOther Medicinal Uses of Charcoal in HumansOther Biochemical and Biological Uses of CharcoalSummary