Zebrafish: A Model for Marine Peptide Based Drug Screening (eBook)
eBook Download:
PDF
2019
|
1st ed. 2019
XI, 73 Seiten
Springer Singapore (Verlag)
978-981-13-7844-7 (ISBN)
XI, 73 Seiten
Springer Singapore (Verlag)
978-981-13-7844-7 (ISBN)
This book offers a comprehensive overview of toxicology, highlighting the significance of peptide-based toxins from marine environments. It discusses the principles of protein-carbohydrate and domain-domain interactions to increase our understanding of toxicology in zebrafish models, as well as drug interaction mechanisms and target definition in drug discovery. It also reviews the structure of marine peptides/toxins and the toxicology of peptide secreting cells and cells that respond to these enzymes, and describes the normal and abnormal toxicology of marine peptides in zebrafish models. Offering insights into the field of proteomics, particularly current practice and research models for solving its many riddles, the book also explains the analytical principles of marine protein-protein and protein-carbohydrate interaction in the context of teratogenicity in target identification in peptide- based drug discovery. Lastly, the book methodically examines the preclinical research on marine proteins/peptides.
This book offers a comprehensive overview of toxicology, highlighting the significance of peptide-based toxins from marine environments. It discusses the principles of protein-carbohydrate and domain-domain interactions to increase our understanding of toxicology in zebrafish models, as well as drug interaction mechanisms and target definition in drug discovery. It also reviews the structure of marine peptides/toxins and the toxicology of peptide secreting cells and cells that respond to these enzymes, and describes the normal and abnormal toxicology of marine peptides in zebrafish models. Offering insights into the field of proteomics, particularly current practice and research models for solving its many riddles, the book also explains the analytical principles of marine protein-protein and protein-carbohydrate interaction in the context of teratogenicity in target identification in peptide- based drug discovery. Lastly, the book methodically examines the preclinical research on marine proteins/peptides.
Dr. Saravanan Ramachandran is an Assistant Professor of Marine Pharmacology at the Faculty of Allied Health Sciences, Chettinad University Chennai, India. He completed his PhD in Marine Biotechnology at Annamalai University, India. His research interests focus on drugs from marine organisms. He has received two research awards from the Indian Council of Medical Research and the Centre for Marine Living Resources and Ecology, Kochi, India, and he has published 40 research articles in international/national journals. He is a member of Society for Biotechnologists (India), International Neurotoxin Association, holds 2 patents and 1 copyright and has submitted 15 gene sequences to the NCBI. Currently, he is serving as the principal investigator of a research project funded by the Govterment of India Department of Biotechnology.
Dr. Senthilkumar Rajagopal is an Assistant Professor at the Department of Biochemistry, School of Life Sciences at Rayalaseema University, Kurnool, India. He completed his PhD in Biochemistry at Annamalai University, India, and his postdoctoral fellowship at various Universities in the USA, including the University of Virginia, Harvard and Virginia Commonwealth University. Dr. Rajagopal is a recipient of the Rameshwardasji Birla Smarak Kosh Endowment award from Mumbai Medical Trust, and the Ramalingaswami Re-entry Fellowship from the Department of Biotechnology, Ministry of Science and Technology, Government of India. His research has addressed protein kinase C modulation of calcium channels currents, and was the principal investigator of a major project entitled 'G-protein coupled receptor mediated intracellular mechanisms by alcohol-induced digestive disorders in the gastrointestinal tract'. Other interests include G-protein coupled receptor signaling pathways in smooth muscle physiology and neurotransmitters transporters to central nervous system. Dr. Rajagopal is a life member of a number of respected scientific associations, such as the Indian Society for Atherosclerosis Research (ISAR), The Indian Science Congress Association (ISCA), Society for Free Radical Research India (SFRR), The Indian Society of Cell Biology (ISCB), the American Association of Pharmaceutical Scientists (AAPS) and the Science Advisory Board (SAB), USA.
This book offers a comprehensive overview of toxicology, highlighting the significance of peptide-based toxins from marine environments. It discusses the principles of protein-carbohydrate and domain-domain interactions to increase our understanding of toxicology in zebrafish models, as well as drug interaction mechanisms and target definition in drug discovery. It also reviews the structure of marine peptides/toxins and the toxicology of peptide secreting cells and cells that respond to these enzymes, and describes the normal and abnormal toxicology of marine peptides in zebrafish models. Offering insights into the field of proteomics, particularly current practice and research models for solving its many riddles, the book also explains the analytical principles of marine protein-protein and protein-carbohydrate interaction in the context of teratogenicity in target identification in peptide- based drug discovery. Lastly, the book methodically examines the preclinical research on marine proteins/peptides.
| Erscheint lt. Verlag | 14.6.2019 |
|---|---|
| Zusatzinfo | XI, 73 p. 39 illus., 29 illus. in color. |
| Sprache | englisch |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie | |
| Medizin / Pharmazie ► Pharmazie | |
| Studium ► 1. Studienabschnitt (Vorklinik) ► Physiologie | |
| Naturwissenschaften ► Biologie ► Zoologie | |
| Schlagworte | Anticancer • marine toxins • pharmacognosy • Teratogenic • Zebrafish |
| ISBN-10 | 981-13-7844-4 / 9811378444 |
| ISBN-13 | 978-981-13-7844-7 / 9789811378447 |
| Haben Sie eine Frage zum Produkt? |
PDF (Wasserzeichen)Größe: 4,1 MB
DRM: Digitales Wasserzeichen
Dieses eBook enthält ein digitales Wasserzeichen und ist damit für Sie personalisiert. Bei einer missbräuchlichen Weitergabe des eBooks an Dritte ist eine Rückverfolgung an die Quelle möglich.
Dateiformat: PDF (Portable Document Format)
Mit einem festen Seitenlayout eignet sich die PDF besonders für Fachbücher mit Spalten, Tabellen und Abbildungen. Eine PDF kann auf fast allen Geräten angezeigt werden, ist aber für kleine Displays (Smartphone, eReader) nur eingeschränkt geeignet.
Systemvoraussetzungen:
PC/Mac: Mit einem PC oder Mac können Sie dieses eBook lesen. Sie benötigen dafür einen PDF-Viewer - z.B. den Adobe Reader oder Adobe Digital Editions.
eReader: Dieses eBook kann mit (fast) allen eBook-Readern gelesen werden. Mit dem amazon-Kindle ist es aber nicht kompatibel.
Smartphone/Tablet: Egal ob Apple oder Android, dieses eBook können Sie lesen. Sie benötigen dafür einen PDF-Viewer - z.B. die kostenlose Adobe Digital Editions-App.
Buying eBooks from abroad
For tax law reasons we can sell eBooks just within Germany and Switzerland. Regrettably we cannot fulfill eBook-orders from other countries.
Mehr entdecken
aus dem Bereich
aus dem Bereich
