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Green Approaches in Medicinal Chemistry for Sustainable Drug Design

Bimal Banik (Herausgeber)

Buch | Softcover
1044 Seiten
2020
Elsevier Science Publishing Co Inc (Verlag)
978-0-12-817592-7 (ISBN)
269,95 inkl. MwSt
Extensive experimentation and high failure rates are a well-recognised downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry reveals how medicinal and green chemistry can work together to directly address this issue.

After providing essential context to the growth of green chemistry in relation to drug discovery in Part 1, the book goes on to identify a broad range of practical methods and synthesis techniques in Part 2. Part 3 reveals how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process, whilst Parts 4 and 5 discuss natural products and microwave-induced chemistry. Finally, the role of computers in drug discovery is explored in Part 6.

Bimal Krishna Banik is a full professor of the Deanship of Research Development at the Prince Mohammad Bin Fahd University in the Kingdom of Saudi Arabia. He was a tenured full professor and first president’s endowed professor at the University of Texas for many years. He also served as the vice president of the Research & Education Development of the Community Health System of Texas. Professor Banik was awarded $7.25 million in grants from the US NIH and US NCI. Importantly, he published more than 600 peer-reviewed papers and 500 presentation abstracts. Notably, he authored and edited 20 books published by Springer, Springer Nature, Nova, Elsevier, De Gruyter, and CRC. He mentored approximately 300 students, 20 postdoctoral fellows, and 7 PhD research scientists. He advised 28 university faculties and 2 students’ organizations that have 1400 students. He chaired 20 symposiums at the American Chemical Society National Meetings and 1 conference at the Nobel Prize Celebration. He served as the editor of 12 journals. He received more than two dozens of national and international awards for teaching, mentoring, advising, public service, overall recognitions, and research.

Part 1: Green Chemistry

Green Chemistry Assisted Synthesis of Natural and Synthetic Compounds as Anticancer Agents

Antibacterial and Antimicrobial Coatings on Metal Substrate by Cold Spray Technique: Present and Future Perspectives

Graphene Oxide Nanosheets as Sustainable Carbocatalysts: Synthesis of Medicinally Important Heterocycles

Sustainable and Green Technologies for Synthesis of Potential Drugs Targeted Towards Tropical Diseases

Clay-Mediated Synthesis of Biologically Active Molecules: Green and Sustainable Approaches

The Role of Ionic Liquid in Medicinal Chemistry

Synthesis of Medicinally Important Heterocycles Inside the Nanoreactors Built in Non-conventional Reaction Media

Green Synthesis of Nanoparticles and Nanocomposites: Medicinal Aspects

Part 2: Methods and Synthesis

Use of Sustainable Organic Transformations in the Construction of Heterocyclic Scaffolds

One-Pot Synthesis of Medicinally Active Compounds

Organocatalytic Cycloaddition Reaction: A Gateway for Molecular Complexity

Diverse Synthesis of Steroids

Reactions in Water: Synthesis of Biologically Active Compounds

Solventless Reactions: Green and Sustainable Approaches in Medicinal Chemistry

Thiosugars in the Synthesis of Biologically Active Compounds

Part 3: Medicinal Chemistry

Implementing Green Chemistry for Synthesis of Cholesterol Lowering Statin Drugs

Sustainable Release of Nanodrugs: A New Biosafe Approach

Stimuli Responsive Sugar-Derived Hydrogels: A Modern Approach in Cancer Biology

Green Synthesis and Biological Evaluation of Anticancer Drugs

Green Chemistry and Synthetic Approaches in the Development of Antidepressant and Antipsychotic agents

Part 4: Natural Products Natural Spices in Medicinal Chemistry: Properties and Benefits

Medicinal Plants and Their Compounds With Anticancer Properties

Part 5: Microwave-Induced Chemistry

Microwave-Assisted Synthesis of Anti-tubercular Agents: A Novel Approach

Microwave-Induced Synthesis of Steroids and Their Chemical Manipulations

Microwave-Induced Synthesis as a Part of Green Chemistry Approach for Novel Anti-inflammatory agents

Part 6: Computers in Drug Discovery

Dipole Moment of Medicinally Active Compounds: A Sustainable Approach

Computational Methods and Tools for Sustainable and Green Approaches in Drug Discovery

Erscheinungsdatum
Reihe/Serie Advances in Green and Sustainable Chemistry
Sprache englisch
Maße 152 x 229 mm
Gewicht 1610 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Naturwissenschaften Chemie Organische Chemie
Naturwissenschaften Chemie Physikalische Chemie
ISBN-10 0-12-817592-3 / 0128175923
ISBN-13 978-0-12-817592-7 / 9780128175927
Zustand Neuware
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