High Pressure Effects in Molecular Biophysics and Enzymology
Oxford University Press Inc (Verlag)
978-0-19-509722-1 (ISBN)
Written by the best researchers in the field, this timely book explores the use of high pressure in connection with spectroscopy as a research tool in biophysics and biochemistry. It covers subjects such as pressure tunning spectroscopy for investigating molecular interactions; high-pressure FT-IR studies of the secondary structure of proteins; structural, functional, and kinetic aspects of nucleic acid-protein complexes with pressure; sequence, salt, charge, and the stability of DNA at high pressure; steady-state enzyme kinetics at high pressure; membrane-free volume with bulky lipid concentration by regular distribution; and pressure and temperature induced inactivation of microorganisms.
1. Resolution of the Ambiguity of Vam't Hoff Plots by the Effect of Pressure Upon the Equilibrium ; 2. Pressure Tunning Spectroscopy - A Tool for Investigating Molecular Interactions ; 3. Use of Partial Molar Volumes of Model Compounds in the Interpretation of High-Pressure Effects on Proteins ; 4. Pressure-tunning Spectroscopy of Proteins: Fourier Transform Infrared Studies in the Diamond Anvil Cell ; 5. Temperature and Pressure-Induced Unfolding of a Mutant of Staphylococcal Nuclease A ; 6. Pressure-Jump Relaxation Kinetics of Unfolding and Refolding Transitions of Staphylococcal Nuclease and Proline Isomerization Mutants ; 7. High-Pressure FT-IR Studies of the Secondary Structure of Proteins ; 8. High-Pressure NMR Studies of the Dissociation of Arc Repressor and the Cold Denaturation of Ribonuclease A ; 9. Exploring Structural, Functional, and Kinetic Aspects of Nucleic Acid-Protein Complexes with Pressure: Nucleosomes and RNA Polymerase ; 10. Pressure and Cold Denaturation of Proteins, Protein-DNA Complexes, and Viruses ; 11. Sequence, Salt, Charge, and the Stability of DNA at High Pressure ; 12. The Application of Pressure Relaxation to the Study of Substrate Binding to Cytochrome P versus Temperature, Pressure, and Viscosity ; 13. Pressure Effects on the Ligand Binding Kinetics for Hemoproteins and Their Site-Directed Mutants ; 14. Steady-State Enzyme Kinetics at High Pressure ; 15. Transient Enzyme Kinetics at High Pressure ; 16. The Effects of High Pressure on the Allosteric Properties of Phosphofructokinase from Escherichia coli ; 17. Correlation Field Splitting of Chain Vibrations: Structure and Dynamics in Lipid Bilayers and Biomembranes ; 18. High Pressure Effects on the Structure and Phase Behavior of Model Membranes Systems ; 19. Membrane-Free Volume with Bulky Lipid Concentration by Regular Distribution: A Functionally Important Membrane Property Explored by Pressure Studies of Pyrene-Labelled Phosphatidylcholine ; 20. NMR Studies of the Order and Dynamics of Dipalmitoylphosphatidylcholine Bilayers as a Function of Pressure ; 21. The Effects of Increased Viscosity on the Function of Integral Membrane Proteins ; 22. Pressure and Temperature Induced Inactivation of Microorganisms ; 23. Osmotic and Hydrostatic Pressure as Tools to Study Molecular Recognition
Erscheint lt. Verlag | 10.10.1996 |
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Zusatzinfo | numerous line figures, tables |
Verlagsort | New York |
Sprache | englisch |
Maße | 164 x 243 mm |
Gewicht | 699 g |
Themenwelt | Naturwissenschaften ► Biologie ► Biochemie |
Naturwissenschaften ► Chemie ► Analytische Chemie | |
Naturwissenschaften ► Physik / Astronomie ► Angewandte Physik | |
ISBN-10 | 0-19-509722-X / 019509722X |
ISBN-13 | 978-0-19-509722-1 / 9780195097221 |
Zustand | Neuware |
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