Phenotypic Screening

Nutrient Stress Small-Molecule Screening Platform for Escherichia coli.- Validation and Development of an Escherichia coli Riboflavin Pathway Phenotypic Screen Hit as a Small-molecule Ligand of the Flavin Mononucleotide Riboswitch.- Phenotypic Screening of Small Molecules with Anti-malarial Activity for Three Different Parasitic Life Stages.- Phenotypic Screening for Inhibitors of a Mutant Thrombopoietin Receptor.- A cell-based Assay for Mitotic Spindle Orientation.- Isolation of Skeletal Muscle Stem Cells for Phenotypic Screens for Modulators of Proliferation.- Cell-based Methods to Identify Inducers of Human Pancreatic Beta-cell Proliferation.- High-content Imaging Phenotypic Screen for Neurogenesis Using Primary Neural Progenitor Cells.- Discovery of Modulators of Adipocyte Physiology Using Fully Functionalized Fragments.- The Ancient Genetic Networks of Obesity: Whole-animal Automated Screening for Conserved Fat Regulators.- Modulation of Threat Response in Larval Zebrafish.- A PLA-iRoCS Pipeline for the Localization of Protein-Protein Interactions in situ.- High-Dimensional Profiling: The Theta Comparative Cell Scoring Method.- Accessing the Open PHACTS Discovery Platform with workflow tools.- Quantitative Prioritization of Tool Compounds for Phenotypic Screening.- A Quantitative Systems Pharmacology Approach to Infer Pathways Involved in Complex Disease Phenotypes.- Phenotype-based High-content Screening using Fluorescent Chemical Bioprobes: Lipid Droplets and Glucose Uptake Quantification in Live Cells.- Developing High-throughput Electrophysiological Assays for Phenotypic Screening.- Testing Susceptibility of Patient Derived Organoid Cultures to Therapies: Pharmacotyping.- Techniques to Enable 1536-well Phenotypic Screening.