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Hemophilia and Von Willebrand's Disease in the 1990s

A New Decade of Hopes and Challenges - Proceedings of the XIX Congress of the World Federation of Hemophilia, Washington, DC, USA, 14-19 August 1990
Buch | Hardcover
530 Seiten
1991
Elsevier Science Ltd (Verlag)
978-0-444-81432-6 (ISBN)
139,65 inkl. MwSt
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There is great enthusiasm and hope - realistic hope - for a cure for hemophilia, as well as for HIV infection. The challenges to bring these hopes to reality are reflected in this book. The papers in this volume represent the authors' views and experience concerning a wide variety of timely issues related to hemophilia, von Willebrand's disease, their treatment and complications. These include musculoskeletal complications, inhibitors, hepatitis and its sequelae, human immunodeficiency virus (HIV) and aquired immunodeficiency syndrome (AIDS), as well as new technologies (and their costs), future strategies including gene insertion, and also global issues related to the basic needs of persons with hemophilia in developing countries.

Hemophilia care around the world. General principles of haemophilia care: Retrospective review and perspectives. Hemophilia care in China. Hemophilia care in Brazil. Developing and maintaining hemophilia program in Thailand. Overall haemophilia problem and the treatment of haemophiliacs in the Indian health care system. Considerations of cost and availability. Global challenges regarding availability and price of coagulation products. Affordable hemophilia treatment: Is a world price structure possible? The introduction of current technologies into underserved international polpulations. A perspective through the FVIII looking glass. Hemophilia in the child. Planning for the future. HIV infection in European children with haemophilia. The hemophilia growth/development study, study design and preliminary findings. The hemophilia growth and developmnt study (HGDS). Hemotherapy: The growing discrepancy between the industrialized and developing world. Present world overview - Industrialized and developing countries. The growing discrepancy in haemotherapy support between the industrialized and developing world. Haemotherapy in India. Hereditary bleeding disorders in the African: Lessons from Kenya. Global impact of HIV on blood transfusion services. Musculoskeletal problems and their management. Late infection of total knee prostheses in HIV positive patients with hemophilia. Orthopaedic surgery in hemophilia patients seropositive for human immunodeficiency virus (HIV): Experiences from 1984-1989. Radiologic evaluation of musculoskeletal problems in hemophilia: Conventional and digital radiography. Arthroscopic evaluation of hemophilic arthropathy. Radiologic evaluation of musculoskeletal problems in hemophilia using CT, MRI and ultrasonography. Periarticular swellings. Percutaneous treatment of haemophilic cysts and pseudotumors. Hemophilic pseudotumor: A report of 25 cases. Hemophilia preoperative assessment for elective orthopedic surgery: A useful protocol or useless paperwork? Protocols in haemophilia treatment: A theoretical method or practical equipment? Physical therapy for bilateral total knee replacement in the hemophilic patient. Gait characteristics in hemophilia. Long-term results of intensive clinical rehabilitation in 21 severe hemophilia patients. Periarticular ossification - The modern therapeutic approach. New plasma derived products for hemophilia. Comparative studies on available clotting factor concentrates. Clotting factor concentrates and immune function. Antihemophilic factor with monoclonal antibodies. Recombinant factor VIII. Recent advances and future prospects. Recombinant DNA technology for the production of factor VIII for the treatment of hemophilia A. Post-translational modification important for factor VIII function. Clinical trials of recombinant Factor VIII. Prospects for gene therapy in hemophilia A and B. Management of factor VIII and factor IX inhibitors. Immune tolerance: A 1990 approach.

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