Genotoxicity Assessment
Humana Press Inc. (Verlag)
978-1-4939-9645-2 (ISBN)
Authoritative and up-to-date, Genotoxicity Assessment: Methods and Protocols, Second Edition serves as a highly useful and ready resource for research students and scientists working in regulatory toxicology as well as biomedical, biochemical, and pharmaceutical sciences.
In Vitro Mouse Lymphoma Cell (L5178Y Tk+/- -3.7.2.C) Forward Mutation Assay.- Erythrocyte-Based Pig-a Gene Mutation Assay.- Detection of In Vivo Mutation in the Hprt and Pig-a Genes of Rat Lymphocytes.- In Vitro Cytogenetic Assays: Chromosomal Aberrations and Micronucleus Tests.- Dicentric Chromosome Assay (DCA) and Cytokinesis-Block Micronucleus (CBMN) Assay in the Field of Biological Dosimetry.- Chromosomal Aberration Test in Human Lymphocytes.- In Vivo Micronucleus Assay in Mouse Bone Marrow.- Micronucleus Cytome Assays in Human Lymphocytes and Buccal Cells.- Micronucleus Analysis by Flow Cytometry.- Hen’s Egg Test for Micronucleus Induction (HET-MN).- Comparative Genomic Hybridization (CGH) in Genotoxicology.- The Comet Assay: Assessment of In Vitro and In Vivo DNA Damage.- The Comet Assay in Human Biomonitoring.- The Comet Assay in Marine Animals.- Multicolour Laser Scanning Confocal Immunofluorescence Microscopy of DNA Damage Response Biomarkers.- Detection of DNA Double Strand Breaks Using Pulse Field Gel Electrophoresis.- Detection of UV-Induced Thymine Dimers.- Micronucleus Assay with Tetrad Cells of Tradescantia.- The Wing-Spot and the Comet Tests as Useful Assays for Detecting Genotoxicity in Drosophila.- In Silico Approaches in Predictive Genetic Toxicology.
Erscheinungsdatum | 20.09.2019 |
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Reihe/Serie | Methods in Molecular Biology ; 2031 |
Zusatzinfo | 57 Illustrations, color; 37 Illustrations, black and white; XI, 378 p. 94 illus., 57 illus. in color. |
Verlagsort | Totowa, NJ |
Sprache | englisch |
Maße | 178 x 254 mm |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie |
Medizin / Pharmazie ► Pharmazie | |
Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
Studium ► 2. Studienabschnitt (Klinik) ► Pharmakologie / Toxikologie | |
Naturwissenschaften ► Chemie ► Technische Chemie | |
Technik ► Umwelttechnik / Biotechnologie | |
Schlagworte | chromosomal abnormalities • Computational predictive models • DNA Damage • Genetic toxicology • Mutation assays • toxicogenomics |
ISBN-10 | 1-4939-9645-2 / 1493996452 |
ISBN-13 | 978-1-4939-9645-2 / 9781493996452 |
Zustand | Neuware |
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