Biochemical Basis and Therapeutic Implications of Angiogenesis -

Biochemical Basis and Therapeutic Implications of Angiogenesis

Buch | Softcover
IX, 548 Seiten
2018 | 2. Softcover reprint of the original 2nd ed. 2017
Springer International Publishing (Verlag)
978-3-319-87008-3 (ISBN)
213,99 inkl. MwSt
Leading authorities on the biochemistry of this complex physiological process explain its critical role in human growth and development as well as the pathogenesis of cancer, heart disease, and other morbidities. The book fully updates the current literature.

This book covers the latest developments in the therapeutic implications of angiogenesis, ranging from angiogenesis in the brain, angiogenesis in cancer, angiogenesis' role in atherosclerosis and heart disease as well as metabolic disorders and peripheral vascular disease. The book is comprehensive in its coverage of angiogenesis in a diverse set of diseases and examines the role of cellular and subcellular structures during the development of angiogenesis. Well-organized and thorough, this is an ideal book for researchers and biomedical engineers working in the field of therapeutic implications of angiogenesis.

This book also:

Covers the basics of the physiology of angiogenesis, including VEGF pathways in angiogenesis, integr

ins in angiogenesis, angiogenesis and exercise physiology, and more

Details the role of angiogenesis in atherosclerosis and heart disease, including vascular endothelial growth factor and atherosclerotic plaque progression as well as angiogenesis and heart failure

Illustrates in detail brain angiogenesis after stroke and the relationship between angiogenesis and Alzheimer's disease

Professor Jawahar L. Mehta is the Stebbins Chair and Professor of Medicine at the College of Medicine, University of Arkansas for Medical Sciences (UAMS). Dr. Naranjan S. Dhalla is the Principal Investigator, Experimental Cardiology at the Institute of Cardiovascular Sciences and is Distinguished Professor in the Faculty of Medicine, Professor of Physiology at the University of Manitoba and Senior Fellow at the Centre for the Advancement of Medicine.

Part1. Molecular Mechanisms in Angiogenesis.- 1.Endothelial Growth Factor Receptors in Angiogenesis.- 2.The Role of Integrins in Angiogenesis.- 3.Toll-Like Receptors in Angiogenesis.- 4.Vascular Stem Cells in Regulation of Angiogenesis.- 5.Role of Transforming Growth Factor Beta Family in Angiogenesis.- 6.Angiogenesis-based Strategy by Hepatocyte Growth Factor for the Treatment of Ischemic Organ Diseases: From Biology to Clinical Trials.- 7.Functions of MicroRNAs in Angiogenesis.- 8.Mast Cells in Angiogenesis. The role of Angiogenic Cytokines.- Part2.Therapeutic Implications of Angiogenesis in Cancer.- 9.Therapeutic Implications of Angiogenesis in Cancer.- 10.The Role of Angiogenesis in Non-small Cell Lung Cancer Tumor Behavior.- 11.Angiogenesis and Prostate Cancer: Friends or Foes.- Part3.Therapeutic Implications of Angiogenesis in Eye Disorders.- 12.Angiogenesis-based Therapies for Eye Diseases.- 13.Anti-Angiogenesis Therapy in Diabetic Retinopathy.- Part4.Therapeutic Implicationsof Angiogenesis in Cardiovascular Disorders and Peripheral Vascular Disease.- 14.Therapeutic Angiogenesis, Cell Therapy and Peripheral Vascular Disease.- 15.Cell-based Therapy in Ischemic Heart Disease.- 16.Angiogenesis and Atherosclerosis.- 17.microRNAs, Angiogenesis and Atherosclerosis.- 18.Trials of Angiogenesis Therapy in Patients with Ischemic Heart Disease.- Part5.Therapeutic Implications of Angiogenesis in Miscellaneous Disease States.- 19.Perspectives in New Advances in Retinal Neovascularization Pathogenesis and Therapeutic Approaches.- 20.Role of Estrogens and Androgens in Angiogenesis.- 21.Brain Angiogenesis after Stroke.- 22.Stimulated Microgravity and Induction of Angiogenesis; A New Perspective in Wound Healing.- 23.Role of Skeletal Muscle Angiogenesis in Peripheral Artery Disease.

Erscheint lt. Verlag 18.8.2018
Reihe/Serie Advances in Biochemistry in Health and Disease
Zusatzinfo IX, 548 p. 62 illus., 55 illus. in color.
Verlagsort Cham
Sprache englisch
Maße 155 x 235 mm
Gewicht 848 g
Themenwelt Medizinische Fachgebiete Innere Medizin Kardiologie / Angiologie
Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Studium 1. Studienabschnitt (Vorklinik) Physiologie
Naturwissenschaften Biologie
Schlagworte angiogenesis • Angiogenesis and Aging • Angiogenesis Atherosclerosis Heart Disease • Angiogenesis Brain • Angiogenesis in Cancer • Angiogenesis Neurology • Angiogenesis Oncology • Angiogenesis Opthalmology • Angiogenesis Peripheral Vascular Disease • Angiogenesis Physiology • Angiogenesis Systemic Sclerosis • Angiogenesis Wound Repair • atherosclerosis • Diabetes Angiogenesis Metabolic Disorders • Ischemic heart disease • receptors
ISBN-10 3-319-87008-4 / 3319870084
ISBN-13 978-3-319-87008-3 / 9783319870083
Zustand Neuware
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