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Antibody–Drug Conjugates – Fundamentals, Drug Development, and Clinical Outcomes to Target Cancer

KJ Olivier (Autor)

Software / Digital Media
560 Seiten
2016
Wiley-Blackwell (Hersteller)
978-1-119-06072-7 (ISBN)
148,75 inkl. MwSt
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Providing practical and proven solutions for antibody-drug conjugate (ADC) drug discovery success in oncology, this book helps readers improve the drug safety and therapeutic efficacy of ADCs to kill targeted tumor cells.

- Discusses the basics, drug delivery strategies, pharmacology and toxicology, and regulatory approval strategies
- Covers the conduct and design of oncology clinical trials and the use of ADCs for tumor imaging
- Includes case studies of ADCs in oncology drug development
- Features contributions from highly-regarded experts on the frontlines of ADC research and development

Kenneth J. Olivier, Jr., PhD, is Head of Toxicology, Discovery Regulatory, Bioanalytical Assay Development, Pharmacokinetics and Discovery Project Management at Merrimack Pharmaceuticals and has over 13 years' experience in the biotechnology and pharmaceutical industries. Sara A. Hurvitz, MD, is an Associate Professor of Medicine at the University of California, Los Angeles (UCLA); Co-Director of the Santa Monica-UCLA Outpatient Oncology Practice; Medical Director of the Clinical Research Unit of the Jonsson Comprehensive Cancer Center of UCLA; and Director of the Breast Oncology Program, Division of Hematology-Oncology, at UCLA.

Erscheint lt. Verlag 3.11.2016
Verlagsort Hoboken
Sprache englisch
Maße 150 x 250 mm
Gewicht 666 g
Themenwelt Naturwissenschaften Biologie
Naturwissenschaften Chemie
ISBN-10 1-119-06072-9 / 1119060729
ISBN-13 978-1-119-06072-7 / 9781119060727
Zustand Neuware
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