Structural Bioinformatics: Applications in Preclinical Drug Discovery Process
Springer International Publishing (Verlag)
978-3-030-05281-2 (ISBN)
The book offers an invaluable resource for graduate and postgraduate students, as well as forresearchers in academic and industrial laboratories working in the areas of chemoinformatics, medicinal and pharmaceutical chemistry and pharmacoinformatics.
Dr. C. Gopi Mohan is an Associate Professor at the Center for Nanosciences and Molecular Medicine, specializing in the areas of structural bioinformatics, structure-based drug design, protein crystallography, and nanoinformatics. He graduated from Banaras Hindu University with a PhD in Physics and gained experience as a postdoctoral researcher at the Indian Institute of Science, Bangalore (India), as a research officer at the University of Bath (UK) and as an associate researcher at the University Henri Poincare, Nancy (France). Further, he worked as a member of the faculty at the National Institute of Pharmaceutical Education & Research (NIPER), Mohali, Punjab. Dr. Gopi Mohan has published more than 70 research papers in refereed journals and was cited as an internationally recognized expert in the field of Structural Bioinformatics and Chemoinformatics by Synergix Ltd. (UK) founded by Dr. N.C. Cohen, a pioneer of rational drug design. Recently he was awarded the ICMR Senior Biomedical Scientist International Fellowship to visit US laboratories for research collaborations.
Free Energy based methods to understand drug resistant mutations.- Structure-based inhibitor design for some multi-targeted drugs and its ADMET profile.- Structure-based drug design in anti-malarial agent identification.- Epigenome - the guide to genomic expression for different diseases.- Structure-based design towards Anti-Alzheimer agents.- Challenges of Structure-based drug design and discovery.
| Erscheinungsdatum | 25.01.2019 |
|---|---|
| Reihe/Serie | Challenges and Advances in Computational Chemistry and Physics |
| Zusatzinfo | XII, 406 p. 106 illus., 79 illus. in color. |
| Verlagsort | Cham |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Gewicht | 789 g |
| Themenwelt | Naturwissenschaften ► Chemie ► Physikalische Chemie |
| Schlagworte | Biomolecular Interactions Drug Design • Computer Aided Drug Design • Computer-aided Molecular Design • Drug Discovery and Development • Drug Discovery Process • Hydrogen Bonding and Protein Active Site • In Silico Molecular Modeling • ligand based drug design • Molecular Docking • Pharmaceutical design • Pharmacoinformatics and Drug Discovery • Predictive Chemoinformatics • Predictive Models Drug Discovery • Protein-Ligand Interactions • Rational drug design • Structural bioinformatics • Structure-Activity Relationships • Structure Based Drug Design • Structure-function relationships • Virtual Screening of Drugs |
| ISBN-10 | 3-030-05281-8 / 3030052818 |
| ISBN-13 | 978-3-030-05281-2 / 9783030052812 |
| Zustand | Neuware |
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