Current Proteomic Approaches Applied to Brain Function

Brain Proteomics: Decoding Neuroproteomes using Mass-Spectrometry.- Applications of Amine-Reactive Tandem Mass Tags (TMT) in Human Neuroproteomics.- Application of Isobaric Tags for Relative and Absolute Quantitation (iTRAQ) to Monitor Olfactory Proteomes during Alzheimer´s Disease Progression.- Protein Microarrays in Neurodegenerative Diseases.- Comprehensive Shotgun Proteomic Analyses of Oligodendrocytes using Ion Mobility and Data Independent Acquisition.- Non-Targeted Brain Lipidomics Profiling Performed by UPLC-ESI-qTOF-MS/MS.- Methods for Human Olfactory Bulb-Tissue Studies using Peptide/Protein MALDI-TOF Imaging Mass Spectrometry (MALDI-IMS).- Neuroproteomics using Short GeLC-SWATH: From the Evaluation of Proteome Changes to the Clarification of Protein Function.- Analysis of Brain Phosphoproteome using Titanium Dioxide Enrichment and High Resolution LC-MS/MS.- N-Glycomics and N-Glycoproteomics of Human Cerebrospinal Fluid.- InVivo Strategies to Isolate and Characterize the Neuronal Ubiquitinated Proteome.- Characterization of the Phosphoproteome and Sialoproteome in Brain Tissues by Mass Spectrometry.- Proteomic Analysis of SUMOylation in the Post-Ischemic Brain.- S-Nitrosylation in Alzheimer´s Disease using Oxidized Cysteine-Selective cPILOT.- Proteomic Analysis of Extracellular Vesicles in Neurological Diseases.- Quantitative In-Depth Profiling of the Postsynaptic Density Proteome to Understand the Molecular Mechanisms Governing Synaptic Physiology and Pathology.- Nuclear Proteomics for Exploring MK-801 Treated Oligodendrocytes to Better Understand Schizophrenia.- Localized Proteomics of Individual Neurons Isolated from Formalin-Fixed, Paraffin Embedded Tissue Sections using Laser Capture Microdissection.- Creation of Reusable Bioinformatics Workflows for Reproducible Analysis of LC-MS Proteomics Data.- Integration of Transcriptomic and Proteomic Data for Disease Insights.