The Nuclear Overhauser Effect

PrefaceAcknowledgmentsIntroductionChapter 1. Nuclear Spin-Lattice Relaxation A. The Nuclear Overhauser Effect B. Relaxation Times C. The Measurement of T1 D. Relaxation of Coupled Spins E. Relaxation of Two Spins F. The Nuclear Overhauser Effect for Two Spins G. Relaxation Times for Two Spins: the 3/2 Effect H. Conclusion ReferencesChapter 2. Mechanisms of Spin-Lattice Relaxation A. The Source of Spin-Lattice Relaxation B. Quadrupole Relaxation C. Intramolecular Dipole-Dipole Relaxation D. Rotational Correlation Times E. Intermolecular Dipole-Dipole Relaxation F. Spin-Rotation Relaxation G. Relaxation by Scalar Coupling H. Relaxation Times of Protons I. Conclusion ReferencesChapter 3. The Nuclear Overhauser Effect in Rigid Molecules A. Relaxation in Multispin Systems B. The Cross-Correlation Problem C. The NOE in Multispin Systems D. Two Spins and Two Groups of Equivalent Spins E. Three Nonequivalent Spins—amx F. The amx3 Case G. Three Spins: Linear H. Three Spins: Acute Case I. Four Spins J. Multispin Systems K. Heteronuclear NOE L. Conclusion ReferencesChapter 4. The Effects of Internal Motions A. Calculation of Enhancements as a Function of Internal Coordinates B. Internal Motions Not Affecting Internuclear Distances C. The Effects of Slow Internal Motions D. The Problem of Interpreting NOE Experiments in the Presence of Internal Motion E. Conclusion ReferencesChapter 5. Experimental Methods A. Sample Preparation B. Sidebands and Modulation C. Magnetic Field Lock D. Homonuclear Double Resonance E. Heteronuclear Double Resonance ReferencesChapter 6. Transient Methods A. Experiments on Two-Spin Systems B. Experiments on Multiple-Spin Systems C. The Fourier Transform Method ReferencesChapter 7. The Effects of Chemical Exchange A. Chemical Exchange Induced Spin-Lattice Relaxation B. Direct Effects of Chemical Exchange: the Transfer of Magnetization between Sites C. A Review of Applications of NOE to Exchanging Systems: Intermolecular Exchange D. A Review of Applications of NOE to Exchanging Systems: Intramolecular Exchange ReferencesChapter 8. Applications of the Nuclear Overhauser Effect: a Review of the Literature A. Assignment of Lines in NMR Spectra B. Determination of Molecular Configuration C. Determination of Molecular Conformation D. Miscellaneous Applications of the NOE ReferencesAppendix I: Tightly Coupled SpinsAppendix II: Mathematical Methods A. Fitting Exponential Functions to Experimental Data B. Numerical Integration C. The Fourier Transform General References ReferencesBibliographyAuthor IndexSubject Index