Clinical Assessment of the Autonomic Nervous System

Editors: Satoshi Iwase, Aichi Medical University, Nagakute, Japan Junichiro Hayano, Nagoya City University, Nagoya, Japan Satoshi Orimo, Kanto Central Hospital, Tokyo, Japan

PART I: Sympathetic Microneurography.-

1 Introduction to Sympathetic Microneurography.-

2 Muscle Sympathetic Nerve Activity in Neurological Disorders.-

3 Muscle Sympathetic Nerve Activity and Cardiovascular Diseases.-

4 Skin sympathetic nerve activity and thermoregulatory control in humans.-

5 Muscle Sympathetic Nerve Activity and Syncope.-

6 Single Fiber Analysis of  Muscle Sympathetic Nerve Activity.-




PART II: Heart Rate Variability (HRV).-





7 Introduction to Heart Rate Variability.-


8 Respiratory Sinus Arrhythmia and Entraining Heartbeats with Cheyne-Stokes Respiration - Cardiopulmonary Works to be Minimal by Synchronizing Heartbeats with Breathing.-

9 Heart RateVariability and Sympathetic Nerve Activity.-

10 Heart Rate Variability and Cardiac Diseases.-

11 Heart-rate Variability and Neurological Disorders.-




PART III: Cardiac MIBG Scintigraphy.-

12 An introduction to MIBG cardiac scintigraphy.-


13 Noradrenaline and 123I-meta-iodobenzylguanidine Kinetics in the Sympathetic Nervous System.- 

14 Technical Considerations for MIBG Cardiac Scintigraphy.-

15 Findings of 123I-MIBG cardiac scintigraphy : Parkinson’s disease and related disorders, and others. (RBD, cardiac diseases, DM, etc).-

16 Findings of MIBG Cardiac Scintigraphy: Dementia with Lewy Bodies and Related Dementia.-

17 Physiological Background of Reduced Cardiac 123I-metaiodobenzylguanidine Uptake.-

18 Pathological background of reduced cardiac MIBG uptake.- 

19 Clinical Implication of Reduced Cardiac MIBG Uptake.