Bone Morphogenetic Proteins

Common Cell Lines Used to Study Bone Morphogenetic Proteins (BMPs).- In Vitro and In Vivo Osteogenic Differentiation of Human Adipose-Derived Stromal Cells.- Cell-based Gene Therapy System for Delivering BMPs.- Generation of Endogenous BMP Transcriptional Reporter Cells through CRISPR/Cas9 Genome Editing.- High-Throughput, Biosensor-based Approach to Examine Bone Morphogenetic Protein (BMP) – Receptor Interactions.- Mutagenesis and Imaging studies of BMP Signaling Mechanisms in C. elegans.- Gene Regulation of BMP Ligands in Drosophila.- Using Amphioxus as a Basal Chordate Model to Study BMP Signaling Pathway.- Proteolytic Activation of Bmps: Analysis of Cleavage in Xenopus Oocytes and Embryos.- Imaging and quantification of P-Smad1/5 in zebrafish blastula and gastrula embryos .- An Adult Zebrafish Model of Fibrodysplasia Ossificans Progressiva.- Generation and Identification of Genetically Modified Mice for BMP Receptors.- Phenotypic Analyses of Genetically Modified Mice for BMP Receptors.- Immunofluorescent Visualization of BMP Signaling Activation on Paraffin-embedded Tissue Sections.- Spatial and Quantitative Detection of BMP Activity in Mouse Embryonic Limb Buds.- Pharmacologic Strategies for Assaying BMP Signaling Function.- Bone Morphogenetic Proteins (BMPs) and Bone Regeneration.- Heterotopic Ossification in Mouse Models of Fibrodysplasia Ossificans Progressiva.- Double-Humanized Mouse Model to Study Bone Morphogenetic Protein (BMP) Signaling in Tumor Xenografts.