Neural Regulation of Metabolism

Dr. Qi Wu is an Assistant Professor at the Department of Pediatrics, USDA Children’s Nutrition Research Center, Baylor College of Medicine in Houston, US. His research focuses on neural circuit control of feeding behavior and complications of metabolic diseases such as obesity, diabetes, mental disorders, and anorexia nervosa, and he has published nearly 30 research articles in this field. Dr. Wu is the Pew Scholar of Biomedical Sciences and the Kavli Scholar. Dr. Ruimao Zheng joined Peking University Health Science Center as a Principal Investigator in 2013. He obtained a Ph.D. in Physiology from Peking University, China and received his postdoctoral training first at the Department of Pharmacology, University of Washington School of Medicine and then at Harvard Medical School and the Stem Cell Institute of Harvard University. His lab now utilizes genetically engineered mouse models in conjunction with optogenetic and chemogenetic approaches, recombinant viral vectors, viral tracing techniques, single-cell transcriptomics, and electrophysiology to decipher the neural nuclei and circuits controlling metabolic homeostasis. Dr. Zheng is an investigator in Peking University’s 100 Talent Program. His research focuses on neuroscience and neural regulation of metabolic and cardiovascular function, and he has published several research articles in these fields. He is a member of several national and international academic neuroscience and metabolism societies. Dr. Zheng is also engaged in teaching and training graduate and postgraduate students at Peking University.

Functional interrogation of the AgRP neural circuits in control of appetite, body weight, and behaviors.- The Leptin Signalings.- The Leptin Resistance.- Neuronal cAMP/PKA Signaling and Energy Homeostasis.- POMC neurons feeding and reward.- Synaptic Regulation of Metabolism.- Glial Regulation of Energy Metabolism.- Regulation of Lipolysis in Adipose Tissue and Clinical Significance.- Electrophysiological mechanism of peripheral hormones and nutrients regulating energy homeostasis.- Central Circadian Clock Regulates Energy Metabolism.- Ghrelin signaling in immunometabolism and inflamm-aging.- Current genetic techniques in neural circuit control of feeding and energy metabolism