Imaging in Movement Disorders

Professor Marios Politis (MD MSc DIC PhD FRCP FEAN) is a Professor of Neurology, Consultant Neurologist, the Director of Neurodegeneration Imaging Group and the Director of Mireille Gillings Neuroimaging Centre at the University of Exeter. His research involves the use of Positron Emission Tomography (PET) and Single Photon Emission Tomography (SPECT) molecular imaging, structural and functional Magnetic Resonance Imaging (MRI), CSF and blood molecular markers, digital markers and clinical observation as methods of investigating aetiology, pathophysiology, and effects and complications of novel therapies in Neurodegenerative disorders. Professor Marios Politis has receive a high number of awards for clinical, research, and clinical research excellence including a research achievement award by the MRC (2010), the Movement Disorder Society Award for Outstanding and Innovative Clinical Research (2012), the IMPETus award for innovative and outstanding PET molecular imaging research (2013, 2014, 2015, 2016) and the PET Investigator Award from the Society of Nuclear Medicine and Molecular Imaging (2015). In 2016, he was elected Fellow of the European Academy of Neurology for outstanding contribution in neurodegenerative research. In 2017, he received the Jon Stolk Award in Movement Disorders from the American Academy of Neurology and was elected Fellow of Royal College of Physicians. Professor Marios Politis has significant industry experience by serving as a clinical investigator, consultant and principal investigator in several collaborations with industrial partners and pharma including a number of clinical trials. He has trained over 120 clinical and non-clinical fellows, research associates and research assistants, and undergraduate and postgraduate students at NIG. He has raised a record amount of over £60 million for cutting-edge research in neurodegenerative conditions such as Parkinson’s disease, Alzheimer’s disease and other neurodegenerative disorders; and is actively collaborating with a high number of philanthropic, government, non-commercial and commercial industrial partners. Professor Marios Politis has published over 150 high impact papers and has been running a specialist Neurology and Movement Disorder clinical service for over 15 years with previous appointments at UCLH, Hammersmith and Charring Cross Hospitals, and King’s College Hospital.

Section 1: Imaging Methodology 1. Advances in PET Methodology Vesna Sossi 2. Advances in MRI Methodology Tayyabah Yousaf, George Dervenoulas and Marios Politis 3. Advances in SPECT Methodology Alberto Cuocolo, Sabina Pappatà, Emilia Zampella and Roberta Assante 4. Hybrid PET/MRI Methodology Marco Aiello, Carlo Cavaliere, Rocco Marchitelli, Antonio d'Albore, Enrico De Vita and Marco Salvatore

Section 2: Imaging Applications in Parkinson's Disease 5. Molecular Imaging of the Dopaminergic System in Idiopathic Parkinson’s Disease Edoardo R. de Natale, Flavia Niccolini, Heather Wilson and Marios Politis 6. Molecular Imaging of the Serotonergic System in Parkinson’s Disease Gennaro Pagano and Marios Politis 7. Molecular Imaging of the Cholinergic System in Parkinson’s Disease Nicolaas I. Bohnen, Prabesh Kanel and Martijn L.T.M. Müller 8. Molecular Imaging of the Noradrenergic System in Idiopathic Parkinson's Disease Adjmal Nahimi, Martin B. Kinnerup, Michael Sommerauer, Albert Gjedde and Per Borghammer 9. Molecular Imaging of Opioid System in Idiopathic Parkinson’s Disease S. Thobois, C. Brefel-Courbon, D. Le Bars and V. Sgambato 10. Molecular Imaging of the Cannabinoid System in Idiopathic Parkinson’s Disease Roberto Cilia 11. Molecular Imaging of Neuroinflammation in Idiopathic Parkinson’s Disease Andreas-Antonios Roussakis and Paola Piccini 12. Molecular Imaging of Addictive Behavior in Idiopathic Parkinson's Disease Christine Ghadery, Mikaeel Valli, Alexander Mihaescu, Rebecca Strafella, Irene Navalpotro, Jinhee Kim and Antonio P. Strafella 13. Structural MRI in Idiopathic Parkinson’s Disease Rosa De Micco, Antonio Russo and Alessandro Tessitore 14. Functional MRI in Idiopathic Parkinson's Disease Massimo Filippi, Sarasso Elisabetta, Noemi Piramide and Federica Agosta