Metallo-Drugs: Development and Action of Anticancer Agents (eBook)

Helmut and Astrid Sigel, University of Basel, Switzerland; Roland K. O. Sigel and Eva Freisinger, University of Zürich, Switzerland.

From the Content: Introduction to the Wider Field of Metallo-Drugs Cisplatin and Oxaliplatin: Our Current Understanding of Their Actions Polynuclear Platinum Drugs: Covalent and Non-covalent DNA-Binding Agents Different Drugs, Different Actions: The Actions and Consequences of Trans and Cationic Platinum Drugs Platinum(IV) Drugs The Ruthenium Drugs KP1019 and NAMI-A: Our Current Understanding of Their Actions Ruthenium Piano-Stool Organometallic Drugs The Gold Drugs Titanium Drugs Vanadium Drugs Non-covalent Metallo-Drugs: Targeting Junction Structures Metallo-Drugs that Target Proteins Non-canonical Nucleic Acid Targets: Metallo-Drugs that Act on Quadruplexes Targeting, Delivery and Nanoscience of Metallo-Drugs Metallo-Intercalators

"The editors are to be congratulated for not only keeping the scientific community abreast of latest developments in this vibrant field of research but for providing an invaluable resource which will no doubt stimulate further cutting edge research in this domain. This volume will also act as an invaluable and indispensable reference source for postgraduate as well as undergraduate teaching. I cannot recommend it highly enough." Celine J. Marmion in: Coordination Chemistry Reviews 371 (2018) 96–98 "(...) Metallo-Drugs: Development and Action of Anticancer Agents is a nice collection of articles that serves a suitable introduction to either the novice or experienced researcher in the field." Seth M. Cohen in: Journal of Inorganic Biochemistry 186 (2018) 103 "Volume 18 of MILS is an excellent update on a vibrant field within Bioinorganic Chemistry, the role of metal species in the treatment of cancer. It reflects both the successes of metallo-drugs in the clinic, their failures and shortcomings, and at the same time also promises and hopes for improved drugs in the future. The book is, as stated by the editors, indeed an “essential resource for scientists in this field” and a valuable source for teachers of relevant Bioinorganic Chemistry courses." Bernhard Lippert in: Inorganica Chimica Acta 479 (2018) 247–248 "(...) This volume currently represents the most up-to-date review within the field of metal-based anticancer agents. (...) A particular strength is the focus on the mechanistic studies and the biological targets, an important feature that makes it different from other reviews recently published. (...) The volume Metallo-Drugs: Development and Action of Anticancer Agents is strongly recommended not only to experienced scientists (either chemists, biologists, biochemists or pharmacologists), but also to researchers in the early stage of their career willing to gain preliminary knowledge on metallodrugs and their biological activity, so as acquire the theoretical background necessary to carry our successful research in the field." Luca Ronconi in: Transition Metal Chemistry 43 (2018) 377–379 "This latest volume of the series on Metal Ions in Life Sciences will be a valuable addition to libraries of researchers and institutions active in cancer research, but also a helpful source for advanced teaching of the subject." Hubert Schmidbaur in: Zeitschrift für Naturforschung B 73 (2018) 355-357