Synthetic Cathinones -

Synthetic Cathinones

Novel Addictive and Stimulatory Psychoactive Substances

Jolanta B. Zawilska (Herausgeber)

Buch | Hardcover
X, 207 Seiten
2018 | 1st ed. 2018
Springer International Publishing (Verlag)
978-3-319-78706-0 (ISBN)
160,49 inkl. MwSt

Over the last decade, and particularly during the recent five years, a rapidly increasing number of novel psychoactive substance (NPSs), often marketed as "designer drugs", "legal highs", "herbal highs", "research or intermediate chemicals" and "laboratory reagents", has appeared on the drug market in an effort to bypass controlled substance legislation. NPSs encompass a wide range of different compounds and drug classes but had been dominated by synthetic cannabinomimetics and psychostimulatory synthetic cathinones, so-called beta-keto amphetamines. Compounds from the later class were first detected in Europe in 2004, and since then 103 new cathinones have been identified and reported to the European Monitoring Centre for Drugs and Drug Addiction, with 57 during the last two years.

Synthetic cathinones - novel addictive and stimulatory psychoactive substances is the first publication of this kind that provides readers with background on chemical structures, detection, prevalence and motivation of use of the very popular group of NPSs. This book also presents comprehensive overview of the mechanisms of action, pharmacological activity, and main metabolic pathways of synthetic cathinones, followed by a detailed discussion of the acute and chronic toxicity associated with the use of these substances. Written by international experts in the field, this multi-authored book is a valuable reference not only for scientists, clinicians and academics, but also for readers representing different professional background who are involved in educational-prophylactic activities directed to harm reduction of psychoactive compounds.

Jolanta Zawilska is Professor at the Academy of Sciences in Lodz, Poland and Chief of the Chronobiology lab at the Centre for Medical Biology. Dr. Zawilska obtained her PhD in Pharmacology  at the Medical University of Lodz. She has over 35 years of experience in pharmacology/pharmacodynamics and chronobiology. She has written numerous publications and has received awards in recognition of her research.

Introduction.- Novel Psychoactive Substances: classification and General Information.- Khat - A Natural Precursor of Synthetic Cathinones.- Analytical Techniques for the Detection of Synthetic Cathinones and Their Metabolites.- Metabolism of Synthetic Cathinones.- Monoamine Transporter and Receptor Interaction Profiles of Synthetic Cathinones.- Effects of Synthetic Cathinones on Brain Neurotransmitters.- Behavioral Profiles and Underlying Transmitters Circuits of Cathinone-Derived Psychostimulant Drugs of Abuse.- Synthetic Cathinones - Prevalence and Motivation of Use.- The Effects and Risks Associated with Synthetic Cathinones Use in Humans.- Concluding Remarks.

Erscheinungsdatum
Reihe/Serie Current Topics in Neurotoxicity
Zusatzinfo X, 207 p.
Verlagsort Cham
Sprache englisch
Maße 155 x 235 mm
Gewicht 487 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Medizin / Pharmazie Studium
Naturwissenschaften Biologie Humanbiologie
Schlagworte addiction • Novel Psychoactive Substances • Recreational drugs • synthetic catinones • Toxicity
ISBN-10 3-319-78706-3 / 3319787063
ISBN-13 978-3-319-78706-0 / 9783319787060
Zustand Neuware
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