Neurobiology of the Placebo Effect Part II

Dr. Luana Colloca is an associate professor at the School of Nursing and School of Medicine, University of Maryland and has extensive experience in the area of pain modulation and placebo effects. Luana received her MD degree from the University of Catanzaro, Medical School and holds both a master degree in Bioethics and a PhD in Neuroscience from the University of Turin in Italy. She completed a post-doc fellowship at the Karolinska Institute in Stockholm, Sweden and a senior research fellowship at the National Institute of Health. Luana's main line of research focuses on how expectations and learning mechanisms shape experience-driven placebo and nocebo effects. The goal of this research is to provide a comprehensive approach to understanding pain modulation and complex functions as such placebo and nocebo effects, incorporating behavioral, pharmacological, functional and psychophysical information directly in humans. The developed approaches are pivotal in translating knowledge about pain modulation from human laboratory settings to patient populations. Luana has authored numerous original articles - well-cited in the biomedical literature and published in journals such as Nature Neuro, JAMA, J Neuro, BMJ, and Pain. Prof. Colloca also co-edited three books for Elsevier, JHP, and Lambert Press respectively on the neurophysiological and translational aspects of the placebo and nocebo effects. Photography Credit: Michael Ciesielski

1. History of placebo effects in medicine Damien Finniss 2. Lumping or Splitting: Towards a Taxonomy of Placebo and Related Effects John M. Kelley 3. Theories and brain mechanisms of placebo analgesia Javeria A. Hashmi 4. Pain modulation: From CPM to placebo and nocebo effects in experimental and clinical pain. Serge Marchand 5. Modulation of the motor system by placebo and nocebo effects. Mirta Fiorio 6. The role of sleep in learning placebo effects Florian Chouchou, Gilles Lavigne, Pierre Rainville and Thien Thanh Dang-Vu 7. Are blue pills better than green? How treatment characteristics modulate the placebo effect Karin Meissner and Klaus Linde 8. Knowledge Gaps in Placebo Research Paul Enck and Katja Weimer 9. The therapeutic value of the relationship in the placebo effect and other healing practices Bruce Wampold 10. Clinical use of placebo effects in patients with pain disorders Regine Klinger 11. The power of labeling in placebo and nocebo effects Kate Faasse and Leslie R. Martin 12. Choose your Words Wisely: The Impact of Message Framing on Patients’ Treatment Preferences and Expectations Paul Glare 13. A review of placebo and active treatment additivity in placebo analgesia Matthew J. Coleshill and Ben Colagiuri 14. Cultivating Placebo to Reduce Pain, Catastrophizing, and Opioid Use Beth D. Darnall 15. Ethics of Placebo Effects Marco Annoni 16. Describing placebo phenomena in medicine Roland Denis Sussex 17. Nocebo responses in brain diseases Dimos Mitsikostas 18. The role of patient-practitioner relationships in placebo and nocebo phenomena Maxie Blasini