Investigation of Nanoscopic Dynamics and Potentials by Interferometric Scattering Microscopy

Jaime Ortega-Arroyo is currently a postdoctoral researcher in Romain Quidant's plasmon nano-optics group at the ICFO (Institute of Photonic Sciences) in Barcelona, Spain. His current research focuses on combining ultrasensitive light microscopy with plasmon-assisted optofluidics. He received his BSc in Chemistry and Mathematics from the University of British Columbia, Vancouver, Canada in 2010, and his PhD in Physical and Theoretical Chemistry from the University of Oxford, UK in 2015, under the guidance of Phillip Kukura.

Introduction.- Non-fluorescent single-molecule approaches to optical microscopy.- Experimental Methods.- Anomalous diffusion due to interleaflet coupling and molecular pinning.- Structural dynamics of myiosin 5a.- All optical label-free detection, imaging and tracking of single proteins.- Single-molecule chemical dynamics: direct observation of physical autocatalysis.- Outlook.