From DNA Photolesions to Mutations, Skin Cancer and Cell Death (eBook)

Chapter 1: UVB and UVA Induced Formation of Photoproducts within Cellular DNA; Chapter 2: Chemical Sequencing Profiles of Photosensitized DNA Damage; Chapter 3: DNA damage induced by UVA radiation: role in solar mutagenesis; Chapter 4: Mutations induced by UV and sunlight; Chapter 5: Mechanisms and Mutagenic Consequences of Photoproduct Bypass by Replicative and DNA Damage Bypass Polymerases; Chapter 6: The Ogg1 Protein of Saccharomyces cerevisiae: Properties and Biological Functions; Chapter 7: The role of a yeast homologue of the human phosphatase activator hPTPA in the cellular response to oxidative DNA damage; Chapter 8: DNA repair in RNA polymerase I transcribed genes; Chapter 9: Global Genome Nucleotide Excision Repair: Key Players and Their Functions; Chapter 10: Efficient Repair of UV-Induced DNA Damage in Terminally Differentiated Human Keratinocytes; Chapter 11: Reactivation of UV-damaged viruses and reporter genes in mammalian cells; Chapter 12: Transcription of p53-regulated genes under transcriptional stress: implications for nucleotide excision repair; Chapter 13: What a difference a wavelength makes: The role of p53 in nucleotide excision repair of UV-induced DNA damage; Chapter 14: p53 and p33ING1: Role in Nucleotide Excision Repair of UV-Damaged DNA; Chapter 15: Nuclear and Non-Nuclear Signals Leading to UV-induced Apoptosis; Chapter 16: Opposing roles of UV-induced apoptosis in early skin cancer; Chapter 17: Acquired activation of signalling pathways in skin tumours from DNA repair-deficient xeroderma pigmentosum patients; Chapter 18: Chaos Theory and Self-Organized Criticality Describe the DNA Damage Signal transduction Network;