Human Cell Transformation

Nuclear Barrier Hypothesis of Aging as Mechanism for Tradeoff Growth to Survival.- Establishment of Cell Lines from the Human Middle and Inner Ear Epithelial Cells.- Cellular Systems for Studying Human Oral Squamous Cell Carcinomas.- Heterotopic Ossification Following Musculoskeletal Trauma: Modeling Stem and Progenitor Cells in Their Microenvironment.- Comparative Proteomic Analysis of Mesenchymal Stem Cells Derived from Human Bone Marrow, Umbilical Cord, and Placenta: Implication in the Migration.- Novel Human Prostate Epithelial Cell Culture Models for the Study of Carcinogenesis and of Normal Stem Cells and Cancer Stem Cells.- Prostate Tumor Cell Plasticity: A Consequence of the Microenvironment.- Role of Epigenetics in Cancer Initiation and Progression.- Cancer Stem Cells, Models of Study and Implications of Therapy Resistance Mechanisms.- The Role of the Basal Stem Cell of the Human Breast in Normal Development and Cancer.- Breast Cancer Subtypes: Two Decades of Journey from Cell Culture to Patients.- Parathyroid Hormone Related Protein (PTHrP) in Tumor Progression.- Mechanism of Radiation Carcinogenesis: Role of the TGFBI Gene and The Inflammatory Signalling Cascade.- Histone Deacetylase Inhibitors: Anti-Neoplastic Agent and Radiation Modulator.- Human Fibroblasts for Large-Scale “Omics” Investigations of ATM Gene Function.- Malignant Transformation of Human Skin Fibroblasts by Two Alternative Pathways.- A Novel Tumor Suppressor, REIC/Dkk-3 Gene Identified By Our In Vitro Transformation Model of Normal Human Fibroblasts Works as a Potent Therapeutic Anti-Tumor Agent.