Genes and Cardiovascular Function

Johann Gregor Mendel “Father of modern genetics”.- Gene therapy: hopes and problems.- VEGFs, FGFs and PDGF coordinate embryonic coronary vascularization.- The E2F pathway in cardiac development and disease.- Cardiac sodium-calcium exchanger expression.- Scleraxis: a new regulator of extracellular matrix formation.- Gender impact on pathophysiology of the heart.- Mitochondrial DNA and heart disease.- A novel algorithm from personal genome to the pathogenic mutant causing      mitochondrial cardiomyopathy.- MELAS Syndrome: mediated by impaired taurinomethyluridine synthesis.- Genetics of myocardial infarction.- Genetic background of myocardial infarction.- I/D ACE polymorphism and cardiovascular risk: disclosed story.- PPARs and myocardial response to ischemia in normal and diseased heart.- Genes and plasma lipids in Czech Slavic population.- Genetic basis of salt-sensitive hypertension in humans.- Gene-environment interactions: their role in hypertension development.- Phenotypic overlap of lethal arrhythmias associated with cardiac sodium mutations: Individual-specific or mutation-specific?.- CLP-1 mediated transcriptional control of hypertrophic gene programs underlying cardiac hypertrophy.- Molecular mechanisms of subcellular remodeling in congestive heart failure.- Cardiomyopathy, sarcomeropathy and Z-discopathy.- Left ventricular assist device: morphological, molecular and genetic changes after  mechanical support.- Vascular Ehlers-Danlos syndrome: a good experimental model is needed for development of treatment strategies.- Multi-scale, multi-physics heart simulator as a tool to link bench and bedside.