Allostery

Binding Techniques to Study the Allosteric Energy Cycle.- Kinetic Trapping of a Key Hemoglobin Intermediate.- Allosteric Coupling Between Transition Metal Binding Sites in Homooligomeric Metal Sensor Proteins.- Studying the Allosteric Energy Cycle by Isothermal Titration Calorimetry.- Detecting “Silent” Allosteric Coupling.- Using Mutant Cycle Analysis to Elucidate Long-Range Functional Coupling in Allosteric Receptors.- A Review of Methods Used for Identifying Structural Changes in a Large Protein Complex.- Allosteric Mechanisms of G Protein-Coupled Receptor Signaling: A Structural Perspective.- Dynamic Light Scattering to Study Allosteric Regulation.- Dissecting the Linkage Between Transcription Factor Self-Assembly and Site-Specific DNA Binding: The Role of the Analytical Ultracentrifuge.- Fluorescence Correlation Spectroscopy and Allostery: The Case of GroEL.- The Morpheein Model of Allostery: Evaluating Proteins as Potential Morpheeins.- Combining NMR and Molecular Dynamics Studies for Insights into the Allostery of Small GTPase-Protein Interactions.- H/D-Exchange Study of an Allosteric Energy Cycle.- Ensemble Properties of Network Rigidity Reveal Allosteric Mechanisms.- An In Vivo Approach to Isolating Allosteric Pathways Using Hybrid Multimeric Proteins.- Mutations in the GABAA Receptor that Mimic the Allosteric Ligand, Etomidate.- Allosteric Regulation of Human Liver Pyruvate Kinase by Peptides that Mimic the Phosphorylated/Dephosphorylated N-Terminus.- In Silico Screening Approaches for Lead Generation: Identification of Novel Allosteric Modulators of Human-Erythrocyte Pyruvate Kinase.- Identification of Allosteric-Activating Drug Leads for Human Liver Pyruvate Kinase.- A Critical Evaluation of Correlated Mutation Algorithms and Coevolution Within Allosteric Mechanisms.- The Advantage ofGlobal Fitting of Data Involving Complex Linked Reactions.- Predicting Binding Sites by Analyzing Allosteric Effects.