Myogenesis in Development and Disease

Dr. David Sassoon received his Ph.D.in Biology from Columbia University (New York, NY) in 1986 for his studies on behavior and muscle/brain function. He subsequently performed his postdoctoral research at the Pasteur Institute (Paris, France) where he worked on the molecular and developmental pathway by which early lineage commitment occurs for skeletal muscle. In 1988, he was appointed Assistant Professor at Boston University Medical School (Boston, MA) and in 1992, he joined the Brookdale Center for Developmental Biology at Mt. Sinai School of Medicine-NYU where he became Full Professor. In 2006, he became a Unit Head (Chair) of an new department focused upon regenerative medicine at the INSERM-University of Pierre and Marie Curie-Sorbonne at the Pitié Hospital and continues to run a research team focused upon adult stem cells in heart, muscle and vascular tissues. He has coordinated several large multipartner consortiums based in Europe and the USA and presently is a coordinator of a Leducq Trans-Atlantic Network.

1. "What Did Maxwell’s Equations Really Have to Do With Edison’s Invention?": Addressing the Complexity of Developing Clinical Interventions for Skeletal Muscle Disease Jonathan Dando 2. The Muscle Stem Cell Niche in Health and Disease Omid Mashinchian, Addolorata Pisconti, Emmeran Le Moal and C. Florian Bentzinger 3. Translational Control of the Myogenic Program in Developing, Regenerating, and Diseased Skeletal Muscle Ryo Fujita and Colin Crist 4. The Composition, Development, and Regeneration of Neuromuscular Junctions Wenxuan Liu and Joe V. Chakkalakal 5. Cellular Biomechanics in Skeletal Muscle Regeneration Edward W. Li, Olivia C. McKee-Muir and Penney M. Gilbert 6. Satellite Cell Self-Renewal Lorenzo Giordani, Alice Parisi and Fabien Le Grand 7. "Known Unknowns": Current Questions in Muscle Satellite Cell Biology Dawn D.W. Cornelison 8. Epigenetic Regulation of Adult Myogenesis Daniel C.L. Robinson and Francis J. Dilworth 9. Dysregulated Myogenesis in Rhabdomyosarcoma Peter Y. Yu and Denis C. Guttridge 10. Muscle Stem Cells and Aging Andrew Brack and Ara B. Hwang