Duchenne Muscular Dystrophy
Humana Press Inc. (Verlag)
978-1-4939-7373-6 (ISBN)
Authoritative and practical, Duchenne Muscular Dystrophy: Methods and Protocols serves as a guide for researchers exploring the complicated nature of dystrophin in the hope of helping the victims of this disorder.
An Overview of Recent Therapeutics Advances for Duchenne Muscular Dystrophy.- Clinical Manifestations and Overall Management Strategies for Duchenne Muscular Dystrophy.- Cardiac Involvement in Duchenne Muscular Dystrophy and Related Dystrophinopathies.- Characterization of the Inflammatory Response in Dystrophic Muscle Using Flow Cytometry.- Imaging Analysis of the Neuromuscular Junction in Dystrophic Muscle.- System Biology Approach: Gene Network Analysis for Muscular Dystrophy.- Proteomic Profiling of the Dystrophin-Deficient Brain.- Probing the Pathogenesis of Duchenne Muscular Dystrophy Using Mouse Models.- Exon Skipping Therapy Using Phosphorodiamidate Morpholino Oligomers in the mdx52 Mouse Model of Duchenne Muscular Dystrophy.- Designing Effective Antisense Oligonucleotides for Exon Skipping.- Identification of Splicing Factors Involved in DMD Exon Skipping Events Using an In Vitro RNA Binding Assay.- The Use of Antisense Oligonucleotides for the Treatment of Duchenne Muscular Dystrophy.- PMO Delivery System Using Bubble Liposomes and Ultrasound Exposure for Duchenne Muscular Dystrophy Treatment.- Proton Nuclear Magnetic Resonance (1H NMR) Spectroscopy-Based Analysis of Lipid Components in Serum / Plasma of Patients with Duchenne Muscular Dystrophy (DMD).- Test of Anti-Fibrotic Drugs in a Cellular Model of Fibrosis Based on Muscle-Derived Fibroblasts from Duchenne Muscular Dystrophy Patients.- Flow Cytometry-Defined CD49d Expression in Circulating T-Lymphocytes is a Biomarker for Disease Progression in Duchenne Muscular Dystrophy.- Advanced Methods to Study the Cross-Talk Between Fibro-Adipogenic Progenitors and Muscle Stem Cells.- AAV6 Vector Production and Purification for Muscle Gene Therapy.- From gRNA Identification to the Restoration of Dystrophin Expression: A Dystrophin Gene Correction Strategy for Duchenne Muscular Dystrophy Mutations Using the CRISPR-Induced Deletion Method.
Erscheinungsdatum | 01.11.2017 |
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Reihe/Serie | Methods in Molecular Biology ; 1687 |
Zusatzinfo | 34 Illustrations, color; 15 Illustrations, black and white; XII, 287 p. 49 illus., 34 illus. in color. |
Verlagsort | Totowa, NJ |
Sprache | englisch |
Maße | 178 x 254 mm |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Orthopädie |
Medizin / Pharmazie ► Studium | |
Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie | |
Schlagworte | Cardiac muscles • DMD • drug discovery • Dystrophin expression • Exon skipping • Skeletal muscle • Targeted molecular treatments |
ISBN-10 | 1-4939-7373-8 / 1493973738 |
ISBN-13 | 978-1-4939-7373-6 / 9781493973736 |
Zustand | Neuware |
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