Neuroepigenomics in Aging and Disease (eBook)

Raúl Delgado-Morales holds a PhD in Neuroscience. He completed his doctoral studies at the Universitat Autònoma de Barcelona working on the field of epigenetics on depression. He continued his research as a postdoc at the Max Planck Institute of Psychiatry in Munich. Dr. Delgado-Morales currently works as a postdoctoral researcher at the Bellvitge Biomedical Research Institute (IDIBELL), in Barcelona, Spain in the field of neuroepigenomics.

Part I: Neurodevelopmental and Childhood Disorders.- MECP2, a modulator of Neuronal Chromatin Organization Involved in Rett Syndrome.- The Role of Noncoding RNAs in Neurodevelopmental Disorders: The Case of Rett Syndrome.- Rubinstein-Taybi Syndrome and Epigenetic Alterations.- Epigenetics of Autism Spectrum Disorder.- Part II: Adolescence Brain Diseases.- Eating Disorders and Epignetics.- Drug Addiction and DNA Modifications.-Drug Addiction and Histone Code Alterations.- Anxiety and Epigenetics.- Part III: Brain Disorders During Adulthood.- Histone Modifications in Major Depressive Disorder and Related Rodent Models.- DNA Methylation in Major Depressive Disorder.- Non-Coding RNAs in Depression.- DNA Methtlation in Schizophrenia.- Histone Post-translational Modifications in Schizophrenia.- Epigenetic Mechanisms of Gene Regulation in Amyotrophic Lateral Sclerosis (ALS).- Epigenetics of Huntington’s Disease.- Part IV:  Elderly Disorders.-DNA Modifications and Alzheimer’s Disease.- Alzheimer’s Disease and Histone Code Alterations.- Alzheimer’s Disease and ncRNAs.- Epigenetics in Parkinson’s Disease.- Part V: New Approaches for Neuroepigenomic Studies.- Single Cell Genomics Unravels Brain Cell Type Complexity.- Epigenome Editing in the Brain.- Techniques for Single Molecule mRNA Imaging in Living Cells.- Stem Cell Technology for (epi)genetic Brain Disorders.- Technologies for Deciphering Epigenomic DNA Patterns.- Bioinformatics Tools for Genome Wide Epigenetic Research.