Ribonucleases

Structures and Functions

Giuseppe D'Alessio, James F. Riordan (Herausgeber)

Buch | Hardcover

670 Seiten

1997
Academic Press Inc (Verlag)
978-0-12-588945-2 (ISBN)

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This volume provides an overview and analysis of specific members of the ribonuclease superfamily of related proteins with functions ranging from tumour growth and tumour inhibition to self-recognition and neurotoxicity.

Pancreatic ribonuclease, the focus of highly productive scientific research for more than half a century and the only enzyme to be the basis of four Nobel prizes, has recently undergone a resurgence in popularity for the recognition of an extended ribonuclease superfamily with functions ranging from tumour growth and inhibition to self-recognition and neurotoxicity. This volume highlights the functional diversity of ribonucleases and reveals the emerging research opportunities provided by these enzymes.

Escherichia Coli Ribonucleases: Paradigms for Understanding Cellular RNA Metabolism and Regulation. Barstar and Barnase. Rnase T1/Rnase T2 Family Rnases. Structures and Mechanism of Action of Cytotoxic Ribonuclease I-Sarcin. Plant Ribonucleases. S-Rnases and Other Plant Extracellular Ribonucleases. Evolutionary Reconstructions in the Ribonuclease Family. Evolution of Vertebrate Ribonucleases: Ribonuclease a Superfamily. Pancreatic Ribonucleases. Crystallographic Studies of Ribonuclease Complexes. NMR Solution Structures of Ribonuclease a and Its Complexes with Mono- And Dinucleotides. Seminal Ribonuclease: The Importance of Diversity. Eosinophil-Associated Ribonucleases. Structure and Function of Angiogenin. Antitumor Rnases. 2-5A-Dependent Rnase L: A Regulated Endoribonuclease in the Interferon System. RNA Processing Rnases in Mammalian Cells. Messenger RNA Ribonucleases and Mrna Turnover in Saccharomyces Cerevisae. Ribonuclease Inhibitor. Subject Index.

Erscheint lt. Verlag	11.2.1997
Verlagsort	San Diego
Sprache	englisch
Maße	152 x 229 mm
Gewicht	1140 g
Themenwelt	Naturwissenschaften ► Biologie ► Biochemie
	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
	Naturwissenschaften ► Biologie ► Zellbiologie
ISBN-10	0-12-588945-3 / 0125889453
ISBN-13	978-0-12-588945-2 / 9780125889452
Zustand	Neuware