Candida albicans: Cellular and Molecular Biology (eBook)

Rajendra Prasad (Herausgeber)

eBook Download: PDF
2017 | 2nd ed. 2017
XII, 554 Seiten
Springer International Publishing (Verlag)
978-3-319-50409-4 (ISBN)

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This book on Candida albicans and similar pathogens provides a timely overview of the groundbreaking discoveries made in the areas of drug resistance, host-pathogen interactions, virulence, host immune system modulation, etc., in the last two decades.

 This comprehensive 2nd Edition includes chapters on fungal infections, hyphal morphogenesis, molecular mechanisms of antifungal resistance, antifungal agents, multidrug transporters, virulence mechanisms in Candida albicans, host-pathogen interactions, the cell wall, fungal biofilms, lipids and antifungal resistance, signaling mechanisms and last but not the least host-immune responses. As such, it offers an ideal reference guide for mycologists, researchers, pharmacists, clinicians, and undergraduate students engaged or interested in fungal research. It will also benefit clinicians, who are required to keep abreast of the current state of research on antifungal drug resistance and antifungal development.



Prof. Rajendra Prasad has recently joined Amity University, Gurgaon as Director of the Amity Institute of Biotechnology and Amity Integrative Sciences and Health. He is a former Professor & Dean of the School of Life Sciences at Jawaharlal Nehru University (JNU), New Delhi, where he served for 40 years in various capacities which included Chairman of Molecular Medicine and Rector (Pro-Vice-Chancellor). Holding a Ph.D. from the Central Drug Research Institute, Lucknow, Prof. Prasad has also served as a visiting professor at several universities and institutes, including the Ecole Normale Superieure - CNRS Paris, France; Catholic University, Louvain-la - Neuve, Belgium; Technical University, Valencia, Spain; Bristol Mayer Squib, Princeton, USA; University of Darmstadt, Germany; and New York Medical College, USA. 

Prof. Prasad is a recipient of the Royal Society Commonwealth Bursary, Alexander von Humboldt-Stiftung Fellowship, Welcome Foundation Grant, and the Mercator Professorship at the University of Bonn. He is an elected fellow of all Indian Science Academies, a European Commission Focal Point Coordinator, and a Research Ambassador, Germany. He is also currently Vice President of the Indian National Science Academy, New Delhi.

Prof. Prasad has published over 225 research papers and has handled 50 national and international grants. He is a leading molecular mycologist and has conducted trendsetting research in the area of antifungal clinical drug resistance.

Prof. Rajendra Prasad has recently joined Amity University, Gurgaon as Director of the Amity Institute of Biotechnology and Amity Integrative Sciences and Health. He is a former Professor & Dean of the School of Life Sciences at Jawaharlal Nehru University (JNU), New Delhi, where he served for 40 years in various capacities which included Chairman of Molecular Medicine and Rector (Pro-Vice-Chancellor). Holding a Ph.D. from the Central Drug Research Institute, Lucknow, Prof. Prasad has also served as a visiting professor at several universities and institutes, including the Ecole Normale Superieure – CNRS Paris, France; Catholic University, Louvain-la – Neuve, Belgium; Technical University, Valencia, Spain; Bristol Mayer Squib, Princeton, USA; University of Darmstadt, Germany; and New York Medical College, USA. Prof. Prasad is a recipient of the Royal Society Commonwealth Bursary, Alexander von Humboldt-Stiftung Fellowship, Welcome Foundation Grant, and the Mercator Professorship at the University of Bonn. He is an elected fellow of all Indian Science Academies, a European Commission Focal Point Coordinator, and a Research Ambassador, Germany. He is also currently Vice President of the Indian National Science Academy, New Delhi. Prof. Prasad has published over 225 research papers and has handled 50 national and international grants. He is a leading molecular mycologist and has conducted trendsetting research in the area of antifungal clinical drug resistance.

1. Fungal infectionsJohn E Edwards1 and Priya Uppuluri2UCLA David Geffen School of Medicine, USA. 1E-mail: jedwards@labiomed.org , 2E-mail: puppuluri@labiomed.org2. Fungal infections- The South-Asian perspectiveArunaloke ChakrabartiDivision of Mycology, Postgraduate Institute of Medical Education & Research, Chandigarh, India. E-mail: arunaloke@gmail.com3. Regulatory pathways during C. albicans infectionsAaron P. MitchellMellon Institute, Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, USA. E-mail: apm1@andrew.cmu.edu4. Virulence mechanisms and regulationChristophe D’EnfertFungal Biology and Pathogenicity Unit - INRA USC2019, Department of Mycology, Institut Pasteur, Paris, France. E-mail: christophe.denfert@pasteur.fr5. Signalling mechanisms in pathogenesis and virulence of C. albicans 6. Biofilm development by C. albicansDavid AndesDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison WI, USA. E-mail: dra@medicine.wisc.edu7. Biofilm development and resistance mechanisms by C. albicansPatrick Van Dijck1 and Mary-Ann Jabra Rizk21 VIB Department of Molecular Microbiology, KU Leuven, Kasteelpark, Arenberg, Leuven, Belgium. 2 University of Maryland School of Dentistry, Maryland, USA. 1E-mail: Patrick.VanDijck@mmbio.vib-kuleuven.be, 2E-mail: MRizk@umaryland.edu8. Biofilm of C. albicans : development and regulationAshraf S. Ibrahim1 and Priya Uppuluri29. Host immune responses during infectionsGordon BrownThe Institute of Medical Sciences, University of Aberdeen, Scotland. E-mail: gordon.brown@abdn.ac.uk10. Mechanism of drug resistance Dominique SanglardInstitute of Microbiology, University Hospital Lausanne and University Hospital Center, Lausanne, Switzerland. E-mail: Dominique.Sanglard@chuv.ch11. Structure- function analyses of Multi-drug transportersRichard D. Cannon Department of Oral Sciences, University of Otago, Dunedin, New Zealand. E-mail: richard.cannon@otago.ac.nz12. All about MFS multi-drug transporter of Candida albicansRajendra Prasad1, Peer Abdul Haseeb Shah2 and Archana Redhu21Amity Institute of Integrative Sciences and Health and Amity Institute of Biotechnology, Amity University, Haryana, India. 2Membrane biology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India. 1E-mail: rp47jnu@gmail.com, rprasad@ggn.amity.edu13. Inhibitors/Modulators of MDR transporters Attilio Di PietroInstitute for the Biology and Chemistry of Protein,  Lyon, France. E-mail : a.dipietro@ibcp.fr14. Inhibitors/Modulators of MDR proteins/transportersBrian MonkDepartment of Oral Sciences, University of Otago, Dunedin, New Zealand. E-mail: brian.monk@otago.ac.nz15.  Anti-fungalsDavid PerlinPublic Health Research Institute Center, New Jersey Medical School - Rutgers, The State University of New Jersey, New Jersey, USA. E-mail: perlinds@umdnj.edu16. Anti-microbial peptidesJoachim Ernst and Marc SwidergallInstitut für Mikrobiologie, Molekulare Mykologie, Heinrich-Heine-Universität, D-40225 Düsseldorf, Germany. E-mail: Joachim.Ernst@uni-duesseldorf.de17.  Anti-candidial agentsSlawomir MilewskiDepartment of Pharmaceutical Technology and Biochemistry, Technical University of Gdańsk, Poland. E-mail: slamilew@pg.gda.pl18. MDR1 and its regulationJoachim MorschhäuserInstitut für Molekulare Infektionsbiologie, Universität Würzburg, Würzburg, Germany.E-mail: joachim.morschhaeuser@uni-wuerzburg.de19.  Genomics and Anti-fungal resistanceKaustuv SanyalMolecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bangalore, India. E-mail: sanyal@jncasr.ac.in20. Genomics and Anti-fungal resistance Judith BermanDept. of Molecular Microbiology & Biotechnology, George Wise Faculty of Life Sciences, Tel Aviv University, Israel. E-mail: Jberman@post.tau.ac.il21.  Lipids and Multi-drug resistance in Candida albicansRajendra Prasad1and Ashutosh Singh21Amity Institute of Integrative Sciences and Health and Amity Institute of Biotechnology, Amity University, Haryana, India. 2Department of Molecular Genetics and Microbiology, Stony Brook University, New York, USA. 1E-mail: rp47jnu@gmail.com, rprasad@ggn.amity.edu, 2E-mail: ashutosh.singh29@gmail.com22.  Cell wall of Candida albicans and its role in virulenceNeil A. R. GowThe Institute of Medical Sciences, University of Aberdeen, Scotland. E-mail: n.gow@abdn.ac.uk23. Hyphal morphogenesis of C. albicansMichael LorenzDepartment of Microbiology and Molecular Genetics, University of Texas Health Science Center, USA. E-mail: Michael.Lorenz@uth.tmc.edu24. Innate immune defences against fungal infectionsMichael YeamanUCLA David Geffen School of Medicine, USA, E-mail: MRYeaman@ucla.edu

Erscheint lt. Verlag 31.1.2017
Zusatzinfo XII, 554 p. 60 illus., 30 illus. in color.
Verlagsort Cham
Sprache englisch
Themenwelt Medizin / Pharmazie
Naturwissenschaften Biologie Genetik / Molekularbiologie
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Technik
Schlagworte antibacterial drug resistance • biofilm development • Candida Species • drug resistance • Fungal Infections • Fungal Resistance • Multi-drug Transporter
ISBN-10 3-319-50409-6 / 3319504096
ISBN-13 978-3-319-50409-4 / 9783319504094
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