Brachytherapy Physics

Preface
List of Contributors

Section I: Fundamentals

Chapter 1 Overview of Brachytherapy Physics
Ravinder Nath, Ph.D.
Chapter 2 Radiobiology: A Briefing for the Brachytherapist
Marco Zaider, Ph.D.
Chapter 3 Sources and Delivery Systems I: Radionuclides
Ravinder Nath, Ph.D.
Chapter 4 LDR Sources: Design and Delivery Systems
Robert E. Wallace, Ph.D.
Chapter 5 Quality Management of Low Dose Rate Brachytherapy Sources
Gary A. Ezzell, Ph.D.
Chapter 6 High Dose Rate Sources and Delivery Systems
Rupak K. Das, Ph.D., and Bruce R. Thomadsen, Ph.D.
Chapter 7 Quality Assurance for High Dose Rate Remote Afterloaders: Safety Standards for Clinical Implementation of High-Activity Brachytherapy Sources
Mark J. Rivard, Ph.D., and Christopher S. Melhus, M.S.
Chapter 8 Continuous Low Dose Rate and Pulsed Dose Rate Remote Afterloader Units
John L. Horton, Ph.D., Ann Lawyer, M.S. and Firas Mourtada, Ph.D.
Chapter 9 An Aperçu of Codes, Directives, Guidances, Notices, and Regulations in Brachytherapy
Glenn P. Glasgow, M.S., Ph.D., F.A.A.P.M., F.A.C.R.
Chapter 10 Brachytherapy Facility Design
Glenn P. Glasgow, M.S., Ph.D., F.A.A.P.M., F.A.C.R.

Section II: Dosimetry
Chapter 11 Calibration for Brachytherapy Sources
Larry A. DeWerd, Ph.D., F.A.A.P.M.
Chapter 12 Localization, Part I: Radiographic Methods and Accuracy
Eugene P. Lief, Ph.D.
Chapter 13 Localization, II: Volume Imaging Techniques and Accuracy for Brachytherapy Dosimetry
Jason Rownd, M.S.
Chapter 14 Semiempirical Dose-Calculation Models in Brachytherapy
Jeffrey F. Williamson, Ph.D.
Chapter 15 Quantitative Dosimetry Methods for Brachytherapy
Jeffrey F. Williamson, Ph.D., and Mark J. Rivard, Ph.D.
Chapter 16 The TG-43 Brachytherapy Dose Calculation Formalism
Mark J. Rivard, Ph.D.
Chapter 17 Treatment Planning Considerations of Brachytherapy Procedures
Ali S. Meigooni, Ph.D., and Robert E. Wallace, Ph.D.

Section III: Interstitial Fundamentals

Chapter 18 Manchester Planar and Volume Implants and the Paris System
Michael T. Gillin, Ph.D., and Firas Mourtada, Ph.D.
Chapter 19 Quimby-Based Brachytherapy Systems
Robert D. Zwicker, Ph.D.
Chapter 20 Implant Design and Execution
Robert D. Zwicker, Ph.D.
Chapter 21 Advanced 3-D Planning
Jean Pouliot, Ph.D., Étienne Lessard, Ph.D. and I-Chow Hsu, M.D.
Chapter 22 Optimization in Brachytherapy
Gary A. Ezzell, Ph.D.
Chapter 23 QA Review of Brachytherapy Treatment Plans
Zuofeng Li, D.Sc.
Chapter 24 Quality Management for Interstitial Implants
Anil Kumar Sharma, PhD.
Chapter 25 Post-Implant Evaluation
William S. Bice, Jr., Ph.D.
Chapter 26 ICRU Recommended Dose and Volume Specifications for Reporting Interstitial Brachytherapy Ali S. Meigooni, Ph.D.
Chapter 27 Intraoperative Radiation Therapy (IORT)
Gil'ad N. Cohen, M.S., and Marco Zaider, Ph.D.

Section IV: Interstitial Applications

A. Applications in Prostate Cancer

Chapter 28 Introduction to Prostate Brachytherapy
Wayne M. Butler, Ph.D., and Gregory S. Merrick, M.D.
Chapter 29 Treatment Planning in Permanent Prostate Brachytherapy
Wayne M. Butler, Ph.D., and Gregory S. Merrick, M.D.
Chapter 30 Treatment Delivery in Prostate LDR Brachytherapy
Eugene P. Lief, Ph.D.
Chapter 31 Post Procedural Evaluation for Prostate Implants
William S. Bice, Jr., Ph.D.
Chapter 32 HDR Brachytherapy for Prostate
Zoubir Ouhib, M.S.
Chapter 33 Modern Advances in Prostate Brachytherapy
Eugene P. Lief, Ph.D.

B. Applications in Cancers of the Head and Neck

Chapter 34 Episcleral Eye Plaques for Treatment of Intraocular Malignancies and Benign Diseases
Sou-Tung Chiu-Tsao, Ph.D.
Chapter 35 Pterygium Brachytherapy Physics
Sou-Tung Chiu-Tsao, Ph.D.
Chapter 36 Brachytherapy for Brain Tumors
Shirish K. Jani, Ph.D. and Patrick Hitchon, M.D.
Chapter 37 Review of Head and Neck Brachytherapy
Zuofeng Li, D.Sc.

C. Applications in Partial Breast Irradiation

Chapter 38 History and Rationale for Accelerated Partial Breast Irradiation (APBI)
Zoubir Ouhib, M.S.
Chapter 39 Breast Interstitial Implant and Treatment Planning
Rupak K. Das, Ph.D. and Rakesh Patel, M.D.
Chapter 40 Partial Breast Irradiation Using the MammoSite® Radiation Therapy System
Wayne M. Butler, Ph.D., and Ernest G. Butler, B.S.

Section V: Intercavitary Applications for Gynecological Cancers

Chapter 41 Brachytherapy for Gynecological Malignancies
John L. Horton, Ph.D
Chapter 42 Volume Imaging in Gynecological Brachytherapy
Bruce R. Thomadsen, Ph.D.
Chapter 43 Applicator Design and Dose Distributions
Jason Rownd, M.S.
Chapter 44 Manchester System for Gynecological Applications
Anil Kumar Sharma, Ph.D.
Chapter 45 Intracavitary Brachytherapy Applicators and UT M.D. Anderson Cancer Center Intracavitary Brachytherapy Techniques
John L. Horton, Ph.D., Ann Lawyer, M.S., Paula Berner, B.S., Mandy Cunningham, B.S., and Firas Mourtada, Ph.D.
Chapter 46 ICRU Reporting for Cervical Brachytherapy
Bruce R. Thomadsen, Ph.D.
Chapter 47 Physics of Uterine Corpus Brachytherapy
Bruce R. Thomadsen, Ph.D.
Chapter 48 Changing from Low Dose Rate to High Dose Rate
Intracavitary Gynecological Brachytherapy
Jason Rownd, M.S.
Chapter 49 Gynecological Interstitial Implants
Anil Kumar Sharma, Ph.D.

D. Application in Vascular Disease

Chapter 50 Intravascular Brachytherapy
Shirish K. Jani, Ph.D., Gerard B. Huppe, M.S., Vincent Massullo, M.D., and Paul Teirstein, M.D.
Section VI: Unconventional Delivery Systems
Chapter 51 Brachytherapy with Miniature Electronic X-ray Sources
Mark J. Rivard, Ph.D., Larry A. DeWerd, Ph.D., and Heather D. Zinkin, M.D.
Chapter 52 Thermal Therapy for Cancer
Paul R. Stauffer, Chris John Diederich, Ph.D., and Jean Pouliot, Ph.D.
Chapter 53 Radiofrequency Ablation
Christopher L. Brace, Ph.D., and Paul F. Laeseke, M.D.
Chapter 54 Microspheres as Microbrachytherapy
Bruce R. Thomadsen, Ph.D., James S. Welsh, Ph.D. and Richard J. Hammes, Ph.D.