Metals in the Brain

Introduction and Overview.- X-Ray Microscopy for Detection of Metals in the Brain.- Imaging Metals in the Brain by Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry.- Fluorescent Probes for the Analysis of Labile Metals in the Brain Cells.- Probing Biological Trace Metals with Fluorescent Indicators.- Microdissection of Brain Tissue to Resolve the Comparative Dissemination of Metal Concentrations in Neurodegenerative Diseases, Focusing on Manganese.- Analysis of Trace Elements and Metalloproteins in Fractionated Human Brain Samples using Size Exclusion Inductively Couples Mass Spectrometry.- Size-Fractionation of Metal Species from Serum Samples for Studying Element Biodistribution in Alzheimer’s Disease.- Lead Uptake and Localization in Glial Cell Cultures.- Evaluating Iron Flux in the Brain.- Current Methods used to Probe and Quantify Intracellular Total and Free Zn(II) Dynamics, and Subcellular Distribution in Cultured Neurons.- Monitoring Intracellular Zn2+ using Fluorescent Sensors: Facts and Artifacts.- Measuring Changes in Brain Manganese or Iron using Magnetic Resonance Imaging (MRI).- Treatment and Measurement of Metals in Brain Cell Cultures.