Nuclear Receptors in Development and Disease

Dr. Douglas Forrest is Senior Investigator at the Laboratory of Endocrinology and Receptor Biology, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) National Institutes of Health (NIH). Sophia Tsai is Professor - Molecular & Cell Biology, at Baylor College of Medicine in Houston, Texas.

1. Evolution of Nuclear Receptors and Ligand Signaling: Towards a Soft Key–Lock Model? 2. The Function and Evolution of Nuclear Receptors in Insect Embryonic Development 3. Nuclear Receptors in Skeletal Homeostasis 4. Estrogen Hormone Biology 5. Mechanisms of Glucocorticoid Action During Development 6. Progesterone Receptor Signaling in Uterine Myometrial Physiology and Preterm Birth 7. Roles of Retinoic Acid in Germ Cell Differentiation 8. Retinoid-Related Orphan Receptor and Transcriptional Control of Neuronal Differentiation 9. Nuclear Receptor TLX in Development and Diseases 10. COUP-TF Genes, Human Diseases, and the Development of the Central Nervous System in Murine Models 11. Genetic Investigation of Thyroid Hormone Receptor Function in the Developing and Adult Brain 12. Resistance to Thyroid Hormone Due to Heterozygous Mutations in Thyroid Hormone Receptor Alpha 13. TR2 and TR4 Orphan Nuclear Receptors: An Overview 14. The Role of COUP-TFII in Striated Muscle Development and Disease