Structure and function of Collagen types

Preface
The Classical Collagens: Types I, II, and III
I. Introduction
II. Early Investigations
III. Electron Microscopic Investigations
IV. Protein Chemical Investigation
V. Biochemical Investigations
VI. The Covalent Structure of the Procollagens
VII. The Gene Structure of Collagens I, II, and III
VIII. Synopsis
References
Type IV Collagen
I. Introduction
II. Structure
III. Molecular Biology
IV. Biosynthesis
V. Immunochemistry
VI. Degradation
VII. Involvement in Disease Processes
VIII. Interactions with Cells and Other Proteins
IX. Appendix A: al(IV) Amino Acid Sequence
X. Appendix B: a2(IV) Amino Acid Sequence
References
Type V Collagen
I. Introduction
II. Compositions of Collagens V
III. Nucleotide Sequences of Procollagens V
IV. Structure of Procollagens V
V. Biosynthesis
VI. Secretion of Procollagens V and Processing
VII. Location of Collagens V in the Extracellular Matrix
VIII. Other Properties of Collagens V
IX. Occurrence of Collagens V
X. Conclusions
References
Type VI Collagen
I. Introduction
II. Protein Chemistry and Macromolecular Organization
III. Biosynthesis
IV. Immunology
V. Tissue Distribution
VI. Possible Functions and Involvement in Disease
References
Type VII Collagen
I. Introduction
II. The Structure of Type VII Collagen
III. The Function of Type VII Collagen
IV. Pathological Findings Related to Disruptions of the Anchoring Fibril Network
References
Type VIII Collagen
I. Introduction
II. Type VIII Collagen from Cells in Culture
III. Type VIII Collagen from Tissue: Descemet's Membrane
IV. Structure of Type VIII Collagen
V. Summary and Conclusions
References
Type IX Collagen
I. Introduction
II. The Pepsin-Resistant Fragments
III. The Intact Type IX Molecule
IV. The Structure of Type IX Collagen
V. Biosynthesis and Cleavage of the Intact Molecule by Proteases
VI. Immunofluorescent Localization of Type IX Collagen in Cartilage Matrix
VII. Summary and Conclusions
References
Type X Collagen
I. Introduction
II. Initial Discovery
III. Source of Type X Collagen
IV. Isolation of Type X Collagen
V. Chromatography of Type X Collagen
VI. Amino Acid Composition of Type X Collagen
VII. Cyanogen Bromide Cleavage of Type X Collagen
VIII. Thermal Stability of Type X Collagen
IX. Vertebrate Collagenase Susceptibility of Type X Collagen
X. Molecular Structure of Type X Collagen
XI. Biosynthesis of Type X Collagen
XII. Immunohistochemical Localization of Type X Collagen with a Monoclonal Antibody
XIII. Biochemical Localization of Type X Collagen
XIV. Functions of Type X Collagen
XV. Unresolved Questions about Type X Collagen
References
Type XI or 1a2a3a Collagen
I. Introduction
II. Nomenclature
III. Isolation and Analysis
IV. Structure
V. Biosynthesis
VI. Protease Susceptibility
VII. Immunochemistry
VIII. Pathology
IX. Possible Functions
References
Analysis of Collagen Structure by Molecular Biology Techniques
I. Introduction
II. Cloning Strategies
III. Strategies for Identifying Collagen cDNA and Genomic Clones
IV. Structural Protein Information that can be Easily Obtained from Cloned DNA
V. Further Use of DNA Probes
VI. Summary and Conclusions
References
Index