Systemic Vasculitides: Current Status and Perspectives (eBook)

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2016 | 1st ed. 2016
XI, 438 Seiten
Springer International Publishing (Verlag)
978-3-319-40136-2 (ISBN)

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In spite of their relatively low prevalence, systemic vasculitides have been the object of intensive basic and clinical investigations over the last few years. As a consequence, important advancements have been achieved: from updated diagnostic and classification criteria and a more rational nomenclature to the recognition of an expanding spectrum of clinical manifestations and potentially devastating complications; from the recognition of the viral etiology of conditions such as HCV-related cryoglobulinemic vasculitis  and HBV-associated polyarteritis nodosa to newly named variable vessel vasculitis exemplified by Behçet's disease; from single-organ vasculitis such as central nervous system vasculitis to the more recently emerging features of the IgG4-related, immune-mediated diseases that are showing remarkable clinical heterogeneity. In addition, intriguing pathogenetic hypotheses are being reported for certain chronic, relapsing vasculitides that are improving our understanding of their biology and basic pathophysiology.  New avenues are being explored that will hopefully allow a deeper comprehension  of the relationships between certain virus-driven vasculitides and lymphoproliferation, and possibly lead to the identification of novel biomarkers that may be used to single out patients at an increased risk of relapse. This explosion of knowledge is obviously resulting in state-of-the-art, personalized treatments of systemic vasculitides.

This book is a collection of reviews on the major vasculitides, written by scientists and clinicians with a multi-year experience in this field. We hope it will provide the reader with a  stimulating container of new advances in scientific knowledge and more rational therapeutic approaches to this fascinating chapter of pathology. 



Franco Dammacco is Emeritus Professor of Internal Medicine at the University of Bari Medical School and has been President of the Italian Society of Internal Medicine. His research and clinical interests include HCV-related cryoglobulinemic vasculitis, onco-hematology, connective tissue diseases and immunodeficiency syndromes. He is author or co-author of more than 470 papers and Editor-in-Chief of the journal Clinical and Experimental Medicine.

Domenico Ribatti is full Professor of Human Anatomy at the University of Bari Medical School. His main research topics are angiogenesis and anti-angiogenesis, with special emphasis for hematological malignancies, tumor microcirculation, and immunological competence.  He is author of over 650 papers  and 8 monographs.

Angelo Vacca is full Professor of Internal Medicine at the University of Bari Medical School and President of the Italian Society of Immunology, Clinical Immunology and Allergology. He is actively involved in research areas such as angiogenesis and tumor progression, multiple myeloma and related malignancies, biological markers of tumor invasion and metastasis, and controlled chemotherapy studies. On these topics he has published over 300 papers.

 

Franco Dammacco is Emeritus Professor of Internal Medicine at the University of Bari Medical School and has been President of the Italian Society of Internal Medicine. His research and clinical interests include HCV-related cryoglobulinemic vasculitis, onco-hematology, connective tissue diseases and immunodeficiency syndromes. He is author or co-author of more than 470 papers and Editor-in-Chief of the journal Clinical and Experimental Medicine. Domenico Ribatti is full Professor of Human Anatomy at the University of Bari Medical School. His main research topics are angiogenesis and anti-angiogenesis, with special emphasis for hematological malignancies, tumor microcirculation, and immunological competence.  He is author of over 650 papers  and 8 monographs. Angelo Vacca is full Professor of Internal Medicine at the University of Bari Medical School and President of the Italian Society of Immunology, Clinical Immunology and Allergology. He is actively involved in research areas such as angiogenesis and tumor progression, multiple myeloma and related malignancies, biological markers of tumor invasion and metastasis, and controlled chemotherapy studies. On these topics he has published over 300 papers.  

SYSTEMIC VASCULITIDES: CURRENT STATUS AND PERSPECTIVES

Editors: Franco Dammacco, Domenico Ribatti, Angelo Vacca

Table of Contents

I. Biology of Blood Vessels, Experimental Models and Nomenclature of Vasculitides

Chapter  1

Morphofunctional Aspects of Endothelium

Domenico Ribatti (Bari, Italy)

Chapter  2

Animal Models of ANCA-Associated Vasculitis

Domenico Ribatti, Franco Dammacco (Bari, Italy)

Chapter  3

Nomenclature of Vasculitides: 2012 Revised International Chapel Hill Consensus Conference    Nomenclature of Vasculitides and Beyond

J. Charles Jennette, Ronald J. Falk, Marco A. Alba (Chapel Hill, NC, USA)

Chapter  4 Search for Autoantibodies in Systemic Vasculitis: is it Useful?

Joice Belem, Bruna Saviol, Alexandre Wagner Silva de Souza (São Paul,  Brasil)Chapter  5Pathogenic Role of ANCA in Small Vessel Inflammation and Neutrophil Function         Giuseppe A. Ramirez, Angelo A. Manfredi (Milan, Italy)

II. Primary Systemic VasculitidesChapter  6

Takayasu Arteritis: When Rarity Maintains the Mystery

Enrico Tombetti, Elena Baldissera, Angelo A. Manfredi, Maria Grazia Sabbadini (Milan, Italy)

Chapter  7

Takayasu Arteritis and Ulcerative Colitis: A Frequent Association?

Chikashi  Terao (Boston, MA, USA)

Chapter  8

Giant Cell Arteritis

Silvia Laura Bosello, Elisa Gremese, Angela Carbonella, Federico Parisi, Francesco Cianci, Gianfranco Ferraccioli (Rome,  Italy)



Chapter  9

HLA System and Giant Cell Arteritis

F. David Carmona, Javier Martín (Granada, Spain)

Chapter  10

Microscopic Polyangiitis

Franco Dammacco, Angelo Vacca (Bari, Italy)

Chapter  11

Granulomatosis with Polyangiitis (Wegener’s)

Franco Dammacco, Sebastiano Cicco, Domenico Ribatti, Angelo Vacca (Bari, Italy)

Chapter  12

Eosinophilic Granulomatosis with Polyangiitis (Churg Strauss Syndrome)

Renato Alberto Sinico, Paolo Bottero (Milan, Italy)

Chapter  13

ANCA-Associated Vasculitis and the Mechanisms of Tissue Injury

Adrian Schreiber, Mira Choi (Berlin, Germany)

Chapter  14

Long-Term Outcome of ANCA-Associated Systemic Vasculitis

James Ritchie, Timothy Reynolds, Joanna Robson (Bristol, U.K.)

Chapter  15

Kawasaki Disease: Past, Present and Future

Fernanda Falcini, Gemma Lepri (Florence, Italy)

Chapter  16 Polyarteritis Nodosa

Nicolò Pipitone, Carlo Salvarani (Reggio Emilia, Italy)

Chapter  17

Anti-Glomerular Basement Membrane Disease

Michele Rossini, Annamaria Di Palma, Vito Racanelli, Franco Dammacco, Loreto   Gesualdo (Bari, Italy) Chapter  18

IgA Vasculitis

Roberta Fenoglio, Dario Roccatello (Turin, Italy)

Chapter  19

Systemic Vasculitis and Pregnancy

Maria Grazia Lazzaroni, Micaela Fredi, Sonia Zatti, Andrea Lojacono, Angela Tincani (Brescia, Italy)

Chapter  20

Behçet Disease

Rosaria Talarico, Stefano Bombardieri (Pisa, Italy)

Chapter  21

Small Vessel Vasculitis of the Skin

Robert G. Micheletti (Philadelphia, PA, USA)

Chapter  22

Adult Primary Central Nervous System Vasculitis

Carlo Salvarani, Robert D. Brown, Jr, Caterina Giannini, Gene G. Hunder

(Reggio Emilia, Italy; Rochester, MN, USA)

Chapter  23

Diagnosis and Therapy of Peripheral Vasculitic Neuropathy

Franz Blaes (Gummersbach, Germany)

Chapter  24

Childhood Uveitis

Alice Brambilla, Rolando Cimaz, Gabriele Simonini (Florence, Italy)

Chapter  25

Cogan’s Syndrome

Rosanna Dammacco (Bari, Italy)

Chapter  26

Non-Infectious Retinal Vasculitis

Shiri Shulman, Zohar Habot- Wilner (Tel Aviv, Israel)

Chapter  27

IgG4-Related Disease

Emanuel Della Torre (Milan, Italy)Chapter  28 Urticarial Vasculitis. A Review of the Literature

Giulia De Feo, Roberta Parente, Chiara Cardamone, Massimo Triggiani (Salerno, Italy)

III. Secondary Vasculitides

Chapter  29

HCV-Related Cryoglobulinemic Vasculitis: an Overview

Franco Dammacco, Sabino Russi, Domenico Sansonno (Bari, Italy)

Chapter  30

Vasculitis In Connective Tissue Diseases

Patrizia Leone, Sebastiano Cicco, Angelo Vacca, Franco Dammacco, Vito Racanelli    (Bari, Italy)Chapter  31

Buerger’s disease (Thromboangiitis Obliterans) Masayuki Sugimoto, Kimihio Komori (Nagoya, Japan)Chapter  32

Cannabis-Associated Vasculitis

Anne Claire Desbois, Patrice Cacoub (Paris, France)IV. Diagnostic and Therapeutic Advances of Systemic Vasculitides

Chapter  33

Imaging in systemic vasculitis

Mazen Abusamaan, Patrick Norton, Klaus Hagspiel, Aditya Sharma

(Charlottesville, VA, USA)Chapter  34 Therapeutic use of biologic agents in systemic vasculitides

John Anthonypillai, Julian L. Ambrus Jr. (Buffalo, NY, USA)Chapter  35

Treatment of ANCA-Associated Vasculitides

Loïc Guillevin (Paris, France)



 

 

Erscheint lt. Verlag 13.10.2016
Zusatzinfo XI, 438 p. 78 illus., 55 illus. in color.
Verlagsort Cham
Sprache englisch
Themenwelt Medizin / Pharmazie Studium
Naturwissenschaften Biologie
Technik
Schlagworte ANCA • Glomerulonephritis • pulmonary infiltration • purpura • vasculitis
ISBN-10 3-319-40136-X / 331940136X
ISBN-13 978-3-319-40136-2 / 9783319401362
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