Systemic Vasculitides: Current Status and Perspectives (eBook)
XI, 438 Seiten
Springer International Publishing (Verlag)
978-3-319-40136-2 (ISBN)
In spite of their relatively low prevalence, systemic vasculitides have been the object of intensive basic and clinical investigations over the last few years. As a consequence, important advancements have been achieved: from updated diagnostic and classification criteria and a more rational nomenclature to the recognition of an expanding spectrum of clinical manifestations and potentially devastating complications; from the recognition of the viral etiology of conditions such as HCV-related cryoglobulinemic vasculitis and HBV-associated polyarteritis nodosa to newly named variable vessel vasculitis exemplified by Behçet's disease; from single-organ vasculitis such as central nervous system vasculitis to the more recently emerging features of the IgG4-related, immune-mediated diseases that are showing remarkable clinical heterogeneity. In addition, intriguing pathogenetic hypotheses are being reported for certain chronic, relapsing vasculitides that are improving our understanding of their biology and basic pathophysiology. New avenues are being explored that will hopefully allow a deeper comprehension of the relationships between certain virus-driven vasculitides and lymphoproliferation, and possibly lead to the identification of novel biomarkers that may be used to single out patients at an increased risk of relapse. This explosion of knowledge is obviously resulting in state-of-the-art, personalized treatments of systemic vasculitides.
This book is a collection of reviews on the major vasculitides, written by scientists and clinicians with a multi-year experience in this field. We hope it will provide the reader with a stimulating container of new advances in scientific knowledge and more rational therapeutic approaches to this fascinating chapter of pathology.Franco Dammacco is Emeritus Professor of Internal Medicine at the University of Bari Medical School and has been President of the Italian Society of Internal Medicine. His research and clinical interests include HCV-related cryoglobulinemic vasculitis, onco-hematology, connective tissue diseases and immunodeficiency syndromes. He is author or co-author of more than 470 papers and Editor-in-Chief of the journal Clinical and Experimental Medicine.
Domenico Ribatti is full Professor of Human Anatomy at the University of Bari Medical School. His main research topics are angiogenesis and anti-angiogenesis, with special emphasis for hematological malignancies, tumor microcirculation, and immunological competence. He is author of over 650 papers and 8 monographs.
Angelo Vacca is full Professor of Internal Medicine at the University of Bari Medical School and President of the Italian Society of Immunology, Clinical Immunology and Allergology. He is actively involved in research areas such as angiogenesis and tumor progression, multiple myeloma and related malignancies, biological markers of tumor invasion and metastasis, and controlled chemotherapy studies. On these topics he has published over 300 papers.
Franco Dammacco is Emeritus Professor of Internal Medicine at the University of Bari Medical School and has been President of the Italian Society of Internal Medicine. His research and clinical interests include HCV-related cryoglobulinemic vasculitis, onco-hematology, connective tissue diseases and immunodeficiency syndromes. He is author or co-author of more than 470 papers and Editor-in-Chief of the journal Clinical and Experimental Medicine. Domenico Ribatti is full Professor of Human Anatomy at the University of Bari Medical School. His main research topics are angiogenesis and anti-angiogenesis, with special emphasis for hematological malignancies, tumor microcirculation, and immunological competence. He is author of over 650 papers and 8 monographs. Angelo Vacca is full Professor of Internal Medicine at the University of Bari Medical School and President of the Italian Society of Immunology, Clinical Immunology and Allergology. He is actively involved in research areas such as angiogenesis and tumor progression, multiple myeloma and related malignancies, biological markers of tumor invasion and metastasis, and controlled chemotherapy studies. On these topics he has published over 300 papers.
SYSTEMIC VASCULITIDES: CURRENT STATUS AND PERSPECTIVES
Editors: Franco Dammacco, Domenico Ribatti, Angelo Vacca
Table of Contents
I. Biology of Blood Vessels, Experimental Models and Nomenclature of Vasculitides
Chapter 1
Morphofunctional Aspects of Endothelium
Domenico Ribatti (Bari, Italy)
Chapter 2
Animal Models of ANCA-Associated Vasculitis
Domenico Ribatti, Franco Dammacco (Bari, Italy)
Chapter 3
Nomenclature of Vasculitides: 2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides and Beyond
J. Charles Jennette, Ronald J. Falk, Marco A. Alba (Chapel Hill, NC, USA)
Chapter 4 Search for Autoantibodies in Systemic Vasculitis: is it Useful?
Joice Belem, Bruna Saviol, Alexandre Wagner Silva de Souza (São Paul, Brasil)Chapter 5Pathogenic Role of ANCA in Small Vessel Inflammation and Neutrophil Function Giuseppe A. Ramirez, Angelo A. Manfredi (Milan, Italy)
II. Primary Systemic VasculitidesChapter 6
Takayasu Arteritis: When Rarity Maintains the Mystery
Enrico Tombetti, Elena Baldissera, Angelo A. Manfredi, Maria Grazia Sabbadini (Milan, Italy)
Chapter 7
Takayasu Arteritis and Ulcerative Colitis: A Frequent Association?
Chikashi Terao (Boston, MA, USA)
Chapter 8
Giant Cell Arteritis
Silvia Laura Bosello, Elisa Gremese, Angela Carbonella, Federico Parisi, Francesco Cianci, Gianfranco Ferraccioli (Rome, Italy)
Chapter 9
HLA System and Giant Cell Arteritis
F. David Carmona, Javier Martín (Granada, Spain)
Chapter 10
Microscopic Polyangiitis
Franco Dammacco, Angelo Vacca (Bari, Italy)
Chapter 11
Granulomatosis with Polyangiitis (Wegener’s)
Franco Dammacco, Sebastiano Cicco, Domenico Ribatti, Angelo Vacca (Bari, Italy)
Chapter 12
Eosinophilic Granulomatosis with Polyangiitis (Churg Strauss Syndrome)
Renato Alberto Sinico, Paolo Bottero (Milan, Italy)
Chapter 13
ANCA-Associated Vasculitis and the Mechanisms of Tissue Injury
Adrian Schreiber, Mira Choi (Berlin, Germany)
Chapter 14
Long-Term Outcome of ANCA-Associated Systemic Vasculitis
James Ritchie, Timothy Reynolds, Joanna Robson (Bristol, U.K.)
Chapter 15
Kawasaki Disease: Past, Present and Future
Fernanda Falcini, Gemma Lepri (Florence, Italy)
Chapter 16 Polyarteritis Nodosa
Nicolò Pipitone, Carlo Salvarani (Reggio Emilia, Italy)
Chapter 17
Anti-Glomerular Basement Membrane Disease
Michele Rossini, Annamaria Di Palma, Vito Racanelli, Franco Dammacco, Loreto Gesualdo (Bari, Italy) Chapter 18
IgA Vasculitis
Roberta Fenoglio, Dario Roccatello (Turin, Italy)
Chapter 19
Systemic Vasculitis and Pregnancy
Maria Grazia Lazzaroni, Micaela Fredi, Sonia Zatti, Andrea Lojacono, Angela Tincani (Brescia, Italy)
Chapter 20
Behçet Disease
Rosaria Talarico, Stefano Bombardieri (Pisa, Italy)
Chapter 21
Small Vessel Vasculitis of the Skin
Robert G. Micheletti (Philadelphia, PA, USA)
Chapter 22
Adult Primary Central Nervous System Vasculitis
Carlo Salvarani, Robert D. Brown, Jr, Caterina Giannini, Gene G. Hunder
(Reggio Emilia, Italy; Rochester, MN, USA)
Chapter 23
Diagnosis and Therapy of Peripheral Vasculitic Neuropathy
Franz Blaes (Gummersbach, Germany)
Chapter 24
Childhood Uveitis
Alice Brambilla, Rolando Cimaz, Gabriele Simonini (Florence, Italy)
Chapter 25
Cogan’s Syndrome
Rosanna Dammacco (Bari, Italy)
Chapter 26
Non-Infectious Retinal Vasculitis
Shiri Shulman, Zohar Habot- Wilner (Tel Aviv, Israel)
Chapter 27
IgG4-Related Disease
Emanuel Della Torre (Milan, Italy)Chapter 28 Urticarial Vasculitis. A Review of the Literature
Giulia De Feo, Roberta Parente, Chiara Cardamone, Massimo Triggiani (Salerno, Italy)
III. Secondary Vasculitides
Chapter 29
HCV-Related Cryoglobulinemic Vasculitis: an Overview
Franco Dammacco, Sabino Russi, Domenico Sansonno (Bari, Italy)
Chapter 30
Vasculitis In Connective Tissue Diseases
Patrizia Leone, Sebastiano Cicco, Angelo Vacca, Franco Dammacco, Vito Racanelli (Bari, Italy)Chapter 31
Buerger’s disease (Thromboangiitis Obliterans) Masayuki Sugimoto, Kimihio Komori (Nagoya, Japan)Chapter 32
Cannabis-Associated Vasculitis
Anne Claire Desbois, Patrice Cacoub (Paris, France)IV. Diagnostic and Therapeutic Advances of Systemic Vasculitides
Chapter 33
Imaging in systemic vasculitis
Mazen Abusamaan, Patrick Norton, Klaus Hagspiel, Aditya Sharma
(Charlottesville, VA, USA)Chapter 34 Therapeutic use of biologic agents in systemic vasculitides
John Anthonypillai, Julian L. Ambrus Jr. (Buffalo, NY, USA)Chapter 35
Treatment of ANCA-Associated Vasculitides
Loïc Guillevin (Paris, France)
Erscheint lt. Verlag | 13.10.2016 |
---|---|
Zusatzinfo | XI, 438 p. 78 illus., 55 illus. in color. |
Verlagsort | Cham |
Sprache | englisch |
Themenwelt | Medizin / Pharmazie ► Studium |
Naturwissenschaften ► Biologie | |
Technik | |
Schlagworte | ANCA • Glomerulonephritis • pulmonary infiltration • purpura • vasculitis |
ISBN-10 | 3-319-40136-X / 331940136X |
ISBN-13 | 978-3-319-40136-2 / 9783319401362 |
Haben Sie eine Frage zum Produkt? |
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