Cystic Fibrosis, Basic and Clinical Research

Screening and prenatal diagnosis Screening and prenatal diagnosis of cystic fibrosis (J.E. Dankert-Roelse). CF cell cultures Role of CFTR in salivary secretion (M.A. McPherson, et al.). The culture of human epithelial cell lines for the study of cystic fibrosis (C.M. Lee). Model systems-sweat glands (P.S. Pedersen). Regulation of the chloride conductance of colonic carcinoma cells (K. Kunzelman, et al.). Metabolism and hyperalimentation Metabolism and hyperalimentation in cystic fibrosis: An overview (J.A. Dodge, A. O'Rawe). Can we improve airway clearance? Can we improve airway clearance? (M.S. Zach). Virulence factors of Pseudomonas aeruginosa The regulation of alginate biosynthesis by mucoid Pseudomonas aeruginosa (N.J. Russell, P.J. Tatnell, P. Gacesa). The multifactorial virulence of Pseudomonas aeruginosa (G. Doring). Role of Pseudomonas aeruginosa lipopolysaccharide and tumor necrosis factor in cystic fibrosis (A. Fomsgaard, N. Hoiby). Extracellular lipase of Pseudomonas aeruginosa : Biochemistry and potential role as a virulence factor (K.-E. Jaeger, D.A. Kinscher, B. Konig, W. Konig). Pore-forming Pseudomonas aeruginosa cytotoxin as a pathogenic factor (F. Lutz, et al.). Prevention and early treatment of Pseudomonas aeruginosa infection Prevention and early treatment of Pseudomonas aeruginosa infection (S.S. Pedersen, C. Koch, N. Hoiby). Treatment of chronic Pseudomonas aeruginosa infection: Effect and side-effects of antibiotics Treatment of chronic Pseudomonas aeruginosa infection in cystic fibrosis: Effects and side-effects of antibiotics (C. Koch, S.S. Pedersen, N. Hoiby). Immunology and vaccines Phase I clinical evaluation of a Pseudomonas aeruginosa alginate-toxin A conjugate vaccine (S.J. Cryz Jr, B. Althaus, J.U. Que). Safety and immunogenicity of an octavalent Pseudomonas aeruginosa O-polysaccharide-toxin A conjugate vaccine in cystic fibrosis patients (U.B. Schaad, et al.). Lung inflammation and anti-inflammatory treatment Lung inflammation and anti-inflammatory treatment (S. Suter). Organ transplantation for CF patients Lung transplantation for cystic fibrosis (M.E. Hodson). Psychosocial aspects The psychosocial situation of independently living CF adults (S. Perobelli). Quality of life after heart-lung transplantation (HLT) (F. Duncan- Skingle). Index of authors.