The Big Book on Small Heat Shock Proteins

Foreword.- 1 The multicolored world of the HSPB family.- 2 Immense implications associated to small stress expression : impacts on human pathologies.- 3 Dynamics-function relationship sof the small Heat shock Proteins.- 4 Insights into how small heat shock proteins bind a great diversity of substrate proteins: a super transformer model.- 5 Model chaperones: small heat shock proteins from plants.- 6 Regulation of the chaperone function of small Hsps.- 7 Redefining the chaperone mechanism of sHsps: not just holdase chaperones.- 8 Everything but the ACD, functional conservation of the non-conserved regions in sHSPs.- 9 HspB6 (Hsp20) as a versatile molecular regulator.- 10 The chloroplast-localized plant sHSP in Arabidopsis thaliana- role of its oligomeric conformation and its translocation into membranes.- 11 Multifunctional roles of crystallin in skeletal and cardiac muscle momeostasis and disease.- 12 Role of small heat shock protein HspB5 in cancer.- 13 Small heat shock proteins and fibrosis.- 14 Neurodegenerative diseases, sex differences and the 27 kDa heat shock protein in the nervous system.- 15 HspB5/B-crystallin in the brain.- 16 Small HSP variants and diseases.- 17 The dynamic duo of small heat proteins and Ifs maintain cell homeostasis, resist cellular stress and enable evolution in cells and tissues.- 18 Regulation of actin-based structure dynamics by HspB proteins and partners.- 19 Heat shock alters keratocyte movement and morphology: exploring a role for HSP17 (HSPB1).- 20 Reconsidering Old Data: Non-Canonical HspB1 Species and the Enigma of the Cytoskeletal Function of HspB1.- 21 Role of HSPB8 in the proteases network: from protein synthesis to protein degradation and beyond.- 22 Understanding what small heat shock proteins do for bacterial cells.- 23 How to stabilize both the proteins and the membranes: diverse effects of sHsps in neuro protection.- 24 Small Heat Shock Proteins and Diapause in the Crustacean, Artemia franciscana.- 25 Drosophila small heat shock proteins: an update on their features and functions.- Index.