Biological Effects of Dietary Restriction

A summary of multidisciplinary research designed to enhance scientific understanding of the practical applications and implications of dietary restriction. The text discusses the effects of dietary restriction on animals, and the implications for human health and safety assessments.

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How does dietary restriction affect the physiological and biochemical state of laboratory animals? How will the present conclusions affect further research? What are the implications for human health and safety assessment? These are the main questions asked in this book by leading international researchers. After an initial look at feeding regimens and the diets of laboratory animals, the book elaborates on a variety of age-associated toxicological and pathological issues, including tumour development. The following sections detail the underlying mechanisms which may induce the broad spectrum of physiological and biochemical changes.