Cortico-Hippocampal Interplay and the Representation of Contexts in the Brain

An exploration of the way in which the brain processes information. The study discusses the limitations of contemporary theories on neural activity and the hippocampal theta rhythm. Many aspects of the theta rhythm are examined, including neuronal sources of control and generation.

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When the cerebral cortex represents the outside world, many small portions of information from that world may be inherently ambiguous; nevertheless, their ambiguity can be resolved if the wider context in which they occur is also specified. It is argued that, using schemes of representation so far envisaged (such as cell assemblies), there are fundamental limitations to the use of contexts to resolve ambiguity, which are set by the limited number of connections each cortical neurone makes with its neighbours. A theory of how the hippocampal theta rhythm can turn populations of neurones in the cerebral cortex into resonant neural activity is developed and discussed in relation to connectional neuroanatomy, innate behaviour, learning of new behaviour and neuronal models of the hippocampus. In addition, many aspects of the theta rhythm are discussed, such as sources of control, neuronal sources of generation, the effect of lesions and neuronal models of the hippocampus.