Stereoelectronic Effects (eBook)

Professor Igor V. Alabugin, Department of Chemistry and Biochemistry, Florida State University, USA Over the last 12 years, Professor Alabugin has published a body of work dedicated to stereoelectronic effects and applied these concepts in practice to the development of new organic reactions. The wide appeal of these concepts is reflected in a large number citations for his papers on the topic (the top three papers have well over 600 citations). His expertise is in broadly defined computational and experimental organic chemistry and its applications to medicinal chemistry and materials science.

1. Introduction

2. Direct Effects of Orbital Overlap on Reactivity

3. Beyond Orbital Overlap: Additional Factors Important For Orbital Interactions

4. Computational and Theoretical Approaches for Studies of Stereoelectronic Effects

5. General Stereoelectronic Trends. Donors, Acceptors and Chameleons

6. Stereoelectronic Effects with Donor and Acceptor Separated By A Single Bond Bridge: The Broad Spectrum of Orbital Contributions to Conformational Analysis

7. Stereoelectronic Effects with Donor and Acceptor Separated By A Vinyl Bridge

8. Remote Stereoelectronic Effects

9. Transition State Stabilization with Stereoelectronic Effects: Stereoelectronic Control of Reaction Bottlenecks

10. Stereoelectronic Effects in Reaction Design

11. Stereoelectronic Effects in Action: The Many Doors Opened By Orbital Interactions

12. Probing Stereoelectronic Effects with Spectroscopic Methods

"This book is highly recommended to every chemist and particularly to every student to work through this book. The higher understanding thus obtained in many chemical fields will be beneficial throughout every phase of chemical education and work. It should furthermore be perfectly suitable as accompanying book for an advanced course on this topic." (Angewandte, 1 February 2017)