Bacterial Pathogenesis

Protein-Based Strategies to Identify and Isolate Bacterial Virulence Factors.- Analysis of Bacterial Surface Interactions with Mass Spectrometry-Based Proteomics.- Differential Radial Capillary Action of Ligand Assay (DRaCALA) for High-Throughput Detection of Protein-Metabolite Interactions in Bacteria.- Identifying Bacterial Immune Evasion Proteins using Phage Display.- Competition for Iron between Host and Pathogen: A Structural Case Study on Helicobacter pylori.- Common Challenges in Studying the Structure and Function of Bacterial Proteins: Case Studies from Helicobacter pylori.- Development of a Single Locus Sequence Typing (SLST) Scheme for Typing Bacterial Species Directly from Complex Communities.- Reconstructing the Ancestral Relationships between Bacterial Pathogen Genomes.- Making Fluorescent Streptococci and Enterococci for Live Imaging.- Computer Vision-Based Image Analysis of Bacteria.- Assessing Vacuolar Escape of Listeria Monocytogenes.- Immobilization Techniques of Bacteria for Live Super-Resolution Imaging using Structured Illumination Microscopy.- Negative Staining and Transmission Electron Microscopy of Bacterial Surface Structures.- Detection of Intracellular Proteins by High-Resolution Immunofluorescence Microscopy in Streptococcus pyogenes.- Antibody Guided Molecular Imaging of Infective Endocarditis Infection.- The Zebrafish as a Model for Human Bacterial Infections.- Determining Platelet Activation and Aggregation in Response to Bacteria.- Killing Bacteria with Cytotoxic Effector Proteins of Human Killer Immune Cells: Granzymes, Granulysin and Perforin.- In Vitro and In Vivo Biofilm Formation by Pathogenic Streptococci.- Murine Mycobacterium marinum Infection as a Model for Tuberculosis.- Generating and Purifying Fab Fragments from Human and Mouse IgG using the Bacterial Enzymes IdeS, SpeB and Kgp.- Measuring Antibody Orientation at the Bacterial Surface.- Towards Clinical use of the IgG Specific Enzymes IdeS and EndoS against Antibody-Mediated Diseases.