Logic Synthesis for Genetic Diseases - Pey-Chang Kent Lin, Sunil P. Khatri

Logic Synthesis for Genetic Diseases

Modeling Disease Behavior Using Boolean Networks
Buch | Softcover
100 Seiten
2016 | Softcover reprint of the original 1st ed. 2014
Springer-Verlag New York Inc.
978-1-4939-5535-0 (ISBN)
106,99 inkl. MwSt
This book brings to bear a body of logic synthesis techniques, in order to contribute to the analysis and control of Boolean Networks (BN) for modeling genetic diseases such as cancer. The authors provide several VLSI logic techniques to model the genetic disease behavior as a BN, with powerful implicit enumeration techniques. Coverage also includes techniques from VLSI testing to control a faulty BN, transforming its behavior to a healthy BN, potentially aiding in efforts to find the best candidates for treatment of genetic diseases.

Introduction.- Part I Inference of Gene Regulatory Networks.- Predictor Set Inference using SAT.- Determining Gene Function in Boolean Networks using SAT.- Predictor Ranking using Modified Zhegalkin Functions.- Part II Intervention of Gene Regulatory Networks.- ATPG for Cancer Therapy.- Summary and Future Work.

Erscheinungsdatum
Zusatzinfo 8 Illustrations, color; 20 Illustrations, black and white; XXI, 100 p. 28 illus., 8 illus. in color.
Verlagsort New York
Sprache englisch
Maße 155 x 235 mm
Themenwelt Informatik Weitere Themen Bioinformatik
Medizin / Pharmazie Physiotherapie / Ergotherapie Orthopädie
Naturwissenschaften Biologie
Technik Elektrotechnik / Energietechnik
Technik Medizintechnik
ISBN-10 1-4939-5535-7 / 1493955357
ISBN-13 978-1-4939-5535-0 / 9781493955350
Zustand Neuware
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