Logic Synthesis for Genetic Diseases
Modeling Disease Behavior Using Boolean Networks
Seiten
2013
Springer-Verlag New York Inc.
978-1-4614-9428-7 (ISBN)
Springer-Verlag New York Inc.
978-1-4614-9428-7 (ISBN)
This book brings to bear a body of logic synthesis techniques, in order to contribute to the analysis and control of Boolean Networks (BN) for modeling genetic diseases such as cancer. The authors provide several VLSI logic techniques to model the genetic disease behavior as a BN, with powerful implicit enumeration techniques. Coverage also includes techniques from VLSI testing to control a faulty BN, transforming its behavior to a healthy BN, potentially aiding in efforts to find the best candidates for treatment of genetic diseases.
Introduction.- Part I Inference of Gene Regulatory Networks.- Predictor Set Inference using SAT.- Determining Gene Function in Boolean Networks using SAT.- Predictor Ranking using Modified Zhegalkin Functions.- Part II Intervention of Gene Regulatory Networks.- ATPG for Cancer Therapy.- Summary and Future Work.
Zusatzinfo | 8 Illustrations, color; 20 Illustrations, black and white; XXI, 100 p. 28 illus., 8 illus. in color. |
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Verlagsort | New York, NY |
Sprache | englisch |
Maße | 155 x 235 mm |
Themenwelt | Informatik ► Weitere Themen ► Bioinformatik |
Mathematik / Informatik ► Mathematik ► Angewandte Mathematik | |
Medizin / Pharmazie ► Physiotherapie / Ergotherapie ► Orthopädie | |
Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
Naturwissenschaften ► Biologie | |
Technik ► Elektrotechnik / Energietechnik | |
Schlagworte | Automatic Test Pattern Generation • Boolean Networks for Genetic Diseases • Boolean Satisfiability • Gene Regulatory Network Extraction • Logic Synthesis • Logic Synthesis for Genetic Diseases • Modeling Disease Behavior • VLSI Logic Synthesis |
ISBN-10 | 1-4614-9428-1 / 1461494281 |
ISBN-13 | 978-1-4614-9428-7 / 9781461494287 |
Zustand | Neuware |
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