Phosphatase Modulators

Chemical Probe Development Versus Drug Development.- Phosphatase High-Throughput Screening Assay Design and Selection.- Multisystemic Functions of Alkaline Phosphatases.- Robotic Implementation of Assays: Tissue-Nonspecific Alkaline Phosphatase (TNAP) Case Study.- Inhibitors of Tissue-Nonspecific Alkaline Phosphatase (TNAP): From Hits to Leads.- A Method for Direct Assessment of Tissue-Nonspecific Alkaline Phosphatase (TNAP) Inhibitors in Blood Samples.- Isolation and Characteristics of Matrix Vesicles.- The Use of Tissue-Nonspecific Alkaline Phosphatase (TNAP) and PHOSPHO1 Inhibitors to Affect Mineralization by Cultured Cells.- Modulators of Intestinal Alkaline Phosphatase.- New Activity Assays for ENPP1 with Physiological Substrates ATP and ADP.- Structure of Acid Phosphatases.- Purification of Prostatic Acid Phosphatase (PAP) for Structural and Functional Studies.- Protein Tyrosine Phosphatases: Structure, Function, and Implication in Human Disease.- High-Throughput Screening for Protein Tyrosine Phosphatase Activity Modulators.- Evaluating Effects of Tyrosine Phosphatase Inhibitors on T Cell Receptor Signaling.- Interactor-Guided Dephosphorylation by Protein Phosphatase-1.- Structure, Regulation, and Pharmacological Modulation of PP2A Phosphatases.